ArticleJournal of magnetic resonance imaging : JMRI2016
Reproducibility and interobserver variability of systolic blood flow velocity and 3D wall shear stress derived from 4D flow MRI in the healthy aorta.
Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed.
- Optimal 4DFlow MR sequence parameters for the assessment of internal carotid artery stenosis: a simulation study.Neuroradiology · 2019Trial
- Postprandial Changes in Thoracic Aortic Flow Detected by 4D Flow MRI May Influence Study Results.Journal of magnetic resonance imaging : JMRI · 2026Article
- Pulmonary artery remodeling and wall shear stress in repaired tetralogy of fallot: insights from 4D flow MRI before and after transcatheter pulmonary valve implantation.The international journal of cardiovascular imaging · 2026Article
- Automated identification, hemodynamic visualisation and quantification of abdominal aortic aneurysms with 4D flow magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2026Article
- Comparing transthoracic echocardiography, 2D and 4D flow cardiovascular magnetic resonance for quantitative valve assessment after percutaneous pulmonary valve implantation.European heart journal. Imaging methods and practice · 2026Article
- Article
- Non-Trileaflet Aortic Valve Aortopathies.Life (Basel, Switzerland) · 2025Review
- The Role of 4D Flow MRI-derived Wall Shear Stress in Aortic Disease: A Comprehensive Review.Reviews in cardiovascular medicine · 2025Review
- Performance of respiratory gated 4D flow MRI with adaptive k-space reordering in healthy controls and aortic dissection: reproducibility and agreement with 2D phase contrast MRI.The international journal of cardiovascular imaging · 2025Article
- Robustness of 4D flow MRI derived aortic wall shear stress and pulse wave velocity across different protocols in healthy controls and in patients with bicuspid aortic valve.The international journal of cardiovascular imaging · 2025Article
- Comparison of Four-Dimensional Flow MRI, Two-Dimensional Phase-Contrast MRI and Echocardiography in Transposition of the Great Arteries.Pediatric cardiology · 2024Article
- Multiyear Interval Changes in Aortic Wall Shear Stress in Patients with Bicuspid Aortic Valve Assessed by 4D Flow MRI.Journal of magnetic resonance imaging : JMRI · 2024Article
- Revolutionizing vascular imaging: trends and future directions of 4D flow MRI based on a 20-year bibliometric analysis.Quantitative imaging in medicine and surgery · 2024Article
- The influence of post-processing software on quantitative results in 4D flow cardiovascular magnetic resonance examinations.Frontiers in cardiovascular medicine · 2024Article
- Influence of aortic valve morphology on vortical structures and wall shear stress.Medical & biological engineering & computing · 2023Article
- Repeatability and reproducibility of various 4D Flow MRI postprocessing software programs in a multi-software and multi-vendor cross-over comparison study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Radiomics-based aortic flow profile characterization with 4D phase-contrast MRI.Frontiers in cardiovascular medicine · 2023Article
- Article
- 4D flow MRI in abdominal vessels: prospective comparison of k-t accelerated free breathing acquisition to standard respiratory navigator gated acquisition.Scientific reports · 2022Article
- The role of 4-dimensional flow in the assessment of bicuspid aortic valve and its valvulo-aortopathies.The British journal of radiology · 2022Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeTo investigate the reproducibility and interobserver variability of 3D aortic velocity vector fields and wall shear stress (WSS) averaged over five systolic timeframes derived from noncontrast 4D flow magnetic resonance imaging (MRI). MATERIALS AND
methodsFourteen controls underwent test-retest 4D flow MRI examinations separated by 16 ± 3 days (resolution = 3.0-3.6 × 2.3-2.6 × 2.5-2.7 mm(3) ; TE/TR/FA = 2.5/4.9 msec/7°; Venc = 150 cm/s). Two observers segmented the aorta, and WSS was calculated for both series of scans and both segmentations. Test-retest and interobserver velocity and WSS vectors were compared on a voxel-by-voxel basis in the aorta and on a regional basis by subdividing the aortas in six segments.
resultsTest-retest: voxel-by-voxel Bland-Altman analysis revealed small differences (-0.03/-0.02 m/s/Pa), limits of agreement (LOA) of 0.25 m/s/0.29 Pa, and coefficients of variation (CV) of 20% for velocity/WSS. Voxel-by-voxel orthogonal regression analysis showed moderate agreement (slope: 1.14/1.16, intraclass correlation coefficient [ICC]: 0.76/0.67 for velocity/WSS). The regional analysis revealed a CV of 9%/8% and ICC of 0.9/0.9 for velocity/WSS. Interobserver: voxel-by-voxel difference for WSS was 0, LOA: 0.17/0.19 Pa, CV: 12/13%, slope: 1.01/1.09, ICC: 0.87/0.85 for test/retest. The CV/ICC for WSS in the regional analysis was 4%/1.0 for test and 3%/1.0 for retest.
conclusionSystolic velocity and WSS derived from 4D flow MRI are reproducible between consecutive visits, with low interobserver variability in healthy volunteers.
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