ArticleJournal of clinical hypertension (Greenwich, Conn.)2015
Is Daytime Systolic Load an Important Risk Factor for Target Organ Damage in Pediatric Hypertension?
Article in Journal of clinical hypertension (Greenwich, Conn.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Prevalence of left ventricular hypertrophy in children and young people with primary hypertension: Meta-analysis and meta-regression.Frontiers in cardiovascular medicine · 2022Pooled it
- Updated Guideline May Improve the Recognition and Diagnosis of Hypertension in Children and Adolescents; Review of the 2017 AAP Blood Pressure Clinical Practice Guideline.Current hypertension reports · 2017Pooled it
- Adenotonsillectomy and Blood Pressure in Children With Mild Obstructive Sleep-Disordered Breathing: An Exploratory Analysis of the PATS Randomized Clinical Trial.JAMA otolaryngology-- head & neck surgery · 2025Trial
- Ambulatory blood pressure monitoring tolerability and blood pressure status in adolescents: the SHIP AHOY study.Blood pressure monitoring · 2019Trial
- Non-Dipping Blood Pressure in Pediatric Hypertension: A Narrative Review.Reviews in cardiovascular medicine · 2026Review
- Blood pressure load associated with progressive kidney function decline in biopsy-proven atherosclerotic chronic kidney disease patients.Clinical and experimental nephrology · 2025Article
- Evaluation of endothelial dysfunction in hypertensive children and adolescents.Pediatric nephrology (Berlin, Germany) · 2024Article
- Evaluation of school achievements in adolescents with primary hypertension.Northern clinics of Istanbul · 2024Article
- Does the Body Mass Index Category Influence Ambulatory Blood Pressure Parameters in Office Normotensive Obese Children?Pediatric cardiology · 2023Article
- Diagnosis of hypertension: Ambulatory pediatric American Heart Association/European Society of Hypertension versus blood pressure load thresholds.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Pediatric Ambulatory Blood Pressure Classification: The Case for a Change.Hypertension (Dallas, Tex. : 1979) · 2021Review
- Gender-Specific Longitudinal Association of Sleep Duration with Blood Pressure among Children: Evidence from CHNS 2004-2015.International journal of hypertension · 2020Article
- Prediction of Ambulatory Hypertension Based on Clinic Blood Pressure Percentile in Adolescents.Hypertension (Dallas, Tex. : 1979) · 2018Article
- Ambulatory Blood Pressure Monitoring in Children and Adolescents: a Review of Recent Literature and New Guidelines.Current hypertension reports · 2017Review
- Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease.Journal of medical biochemistry · 2017Article
- The Use of Ambulatory Blood Pressure Monitoring As Standard of Care in Pediatrics.Frontiers in pediatrics · 2017Review
- Left Ventricular Hypertrophy in Pediatric Hypertension: A Mini Review.Frontiers in pediatrics · 2017Review
- Microalbuminuria in Children With Primary Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2016Article
- Hypertension and End-Organ Damage in Children--Is the Picture Less Fuzzy Now?Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to compare ambulatory blood pressure (BP) monitoring (ABPM) data and determine which hypertension type is a risk factor in target organ damage. A total of 82 children (47 boys) with suspected hypertension based on office BP measurements and considered hypertensive by ABPM were studied. Target organ damage included the following: 35.3% hypertensive retinopathy, 25.6% microalbuminuria, 15.8% increased left ventricular mass index, 29.2% increased carotid intima-media thickness (cIMT), 24.3% high augmentation index (AIx), and 19.5% high pulse wave velocity (PWV). The association between BP load, PWV, and cIMT was statistically significant. There were significant correlations between daytime systolic BP load, PWV, AIx, and cIMT. A statistically significant difference was also detected between nighttime systolic BP load, PWV, and cIMT values and nighttime diastolic BP load levels and values of AIx and cIMT. There was also a statistically significant difference between the high level of nighttime diastolic BP load and cIMT. The authors found that target organ damage was seen more often in children with primary hypertension who had systolic loads.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.