ReviewWorld journal of gastrointestinal endoscopy2015
Endotherapy of leaks and fistula.
Review in World journal of gastrointestinal endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Systematic review of endoluminal vacuum-assisted therapy as salvage treatment for rectal anastomotic leakage.BJS open · 2019Pooled it
- Efficacy and Safety of Stents in the Treatment of Fistula After Bariatric Surgery: a Systematic Review and Meta-analysis.Obesity surgery · 2018Pooled it
- Indigenously modified endoluminal vacuum-assisted closure therapy for post-operative gastrointestinal transmural defects: Case series and review of literature.Journal of minimal access surgery · 2026Article
- Application of endoscopic vacuum-assisted closure therapy for oesophageal perforation: first case report in East Africa.Journal of cardiothoracic surgery · 2026Article
- Therapeutic Intervention in Pediatric Endoscopy: Management of Postsurgical Complications and Bleeding.Visceral medicine · 2025Review
- Endoscopic vacuum assisted closure therapy for esophagopericardial fistula in a 16-year-old male: A case report.World journal of gastrointestinal endoscopy · 2024Article
- Endoscopic Intervention for Anastomotic Leakage After Gastrectomy.Journal of gastric cancer · 2024Review
- A case report of a colouterine fistula treatment: when the patient chooses the steeplechase.Annals of coloproctology · 2023Article
- Endoscopic Vacuum Therapy of Upper Gastrointestinal Anastomotic Leaks: How to Deal with the Challenges (with Video).Life (Basel, Switzerland) · 2023Review
- [Endoscopy on the surgical intensive care unit].Der Anaesthesist · 2021Article
- A pilot human study on newly designed closure clips in endoscopic closure of giant gastrointestinal perforation using a continuous closing method.Surgical endoscopy · 2021Article
- Safety and effectiveness of endoluminal vacuum-assisted closure for esophageal defects: Systematic review and meta-analysis.Endoscopy international open · 2021Review
- Effective Endoscopic Closure of Cholecysto-duodenal and Transverse Colon Fistulas Due to Squamous Cell Carcinoma of the Gallbladder Using Polyglycolic Acid Sheets and a Covered Metal Stent.Internal medicine (Tokyo, Japan) · 2021Article
- Nanocomposite hyaluronic acid-based hydrogel for the treatment of esophageal fistulas.Materials today. Bio · 2021Article
- Postoperative Intestinal Fistula in Primary Advanced Ovarian Cancer Surgery.Cancer management and research · 2021Article
- Use of endoscopic vacuum (E-Vac) therapy for the treatment of a cervical oesophagoileostomy leakage after a right-colon interposition for oesophageal replacement.Gastroenterology report · 2020Article
- The Use of the Overstitch to Close Perforations and Fistulas.Gastrointestinal endoscopy clinics of North America · 2020Review
- Endoscopic vacuum assisted wound closure (EVAC) device to treat esophageal and gastric leaks: assessing time to proficiency and cost.Surgical endoscopy · 2019Article
- Spontaneous Gastrojejunal Fistulization after Roux-en-Y Bypass Surgery: A Case Report and Review of Literature.Cureus · 2019Article
- Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects.World journal of gastrointestinal endoscopy · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perforations, leaks and fistula involving gastrointestinal (GI) tract are increasing encountered in clinical practice. There is a changing paradigm for their management with surgical approach being replaced by conservative approach including endoscopic therapy. Clips (through the scope and over the scope) and covered stent are front runners for endotherapy for GI leaks and fistula. Over the scope clips introduced recently, can treat larger defects compared to through the scope clips. Covered stents are suited for larger defects and those associated with luminal narrowing. However cervical esophagus, gastro-esophageal junction, stomach and right colonic lesions may be better for clip therapy rather than stenting. Recent developments in this field include use of endovac therapy which consists of a sponge with suction device, biodegradable stent, use of fibrin glue and some endo-suturing device. Conservative therapy with no surgical or endoscopic intervention, may be suitable for a small subset of patients. An algorithm based on location, size of defect, associated stricture, infection and available expertise needs to be developed to reduce the mortality and morbidity of this difficult clinical problem.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.