Evidence map›Paper›PMID 26140006›Full record

SynthesisWorld journal of gastroenterology2015

Updated meta-analysis of pancreatic stent placement in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis.

Jin-He Fan, Jun-Bo Qian, Ya-Min Wang, Rui-Hua Shi, Cheng-Jin Zhao

2 registry-linked trialsAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04546867 nacompletednot on this mapstarted 2020, after this paper: background citation

Sonographic Based Visualization Instead of X-ray of Pancreatic Stents Placed to Prenvent Post-ERCP Pancreatitis.

TypeinterventionalSponsorJohann Wolfgang Goethe University HospitalRan2020 to 2023Enrolled88ConditionsPost-ERCP Acute Pancreatitis, Pancreatic Stent, Ultrasound, X-raysArmsSonographic based visualization of a pancreatic stent
NCT05252754 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

A Randomized Trial Comparing Rectal Indomethacin Alone Versus a Combination of Rectal Indomethacin and Oral Tacrolimus for Post-ERCP Pancreatitis Prophylaxis

TypeinterventionalSponsorJohns Hopkins UniversityRan2023 to 2026Enrolled4,874ConditionsPost-ERCP Acute PancreatitisArmsTacrolimus capsule, Placebo, Rectal Indomethacin
3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. [Quality Indicators of Endoscopic Retrograde Cholangiopancreatography in Korea].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. A closer look at universal prophylactic rectal NSAIDs in prevention of post-ERCP pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jin-He FanJin-He Fan, Jun-Bo Qian, Ya-Min Wang, Cheng-Jin Zhao, Department of Gastroenterology, Nantong First People's Hospital, Nantong 226001, Jiangsu Province, China.
Jun-Bo QianJin-He Fan, Jun-Bo Qian, Ya-Min Wang, Cheng-Jin Zhao, Department of Gastroenterology, Nantong First People's Hospital, Nantong 226001, Jiangsu Province, China.
Ya-Min WangJin-He Fan, Jun-Bo Qian, Ya-Min Wang, Cheng-Jin Zhao, Department of Gastroenterology, Nantong First People's Hospital, Nantong 226001, Jiangsu Province, China.
Rui-Hua ShiJin-He Fan, Jun-Bo Qian, Ya-Min Wang, Cheng-Jin Zhao, Department of Gastroenterology, Nantong First People's Hospital, Nantong 226001, Jiangsu Province, China.
Cheng-Jin ZhaoJin-He Fan, Jun-Bo Qian, Ya-Min Wang, Cheng-Jin Zhao, Department of Gastroenterology, Nantong First People's Hospital, Nantong 226001, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the efficacy and safety profile of pancreatic duct (PD) stent placement for prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).

methodsWe performed a search of MEDLINE, EMBASE, and Cochrane Library to identify randomized controlled clinical trials of prophylactic PD stent placement after ERCP. RevMan 5 software provided by Cochrane was used for the heterogeneity and efficacy analyses, and a meta-analysis was performed for the data that showed homogeneity. Categorical data are presented as relative risks and 95% confidence intervals (CIs), and measurement data are presented as weighted mean differences and 95%CIs.

resultsThe incidence rates of severe pancreatitis, operation failure, complications and patient pain severity were analyzed. Data on pancreatitis incidence were reported in 14 of 15 trials. There was no significant heterogeneity between the trials (I(2) = 0%, P = 0.93). In the stent group, 49 of the 1233 patients suffered from PEP, compared to 133 of the 1277 patients in the no-stent group. The results of this meta-analysis indicate that it may be possible to prevent PEP by placing a PD stent.

conclusionPD stent placement can reduce postoperative hyperamylasemia and might be an effective and safe option to prevent PEP if the operation indications are well controlled.

Indexed as

StentsChi-Square DistributionCholangiopancreatography, Endoscopic RetrogradeHumansIncidenceOdds RatioPancreatitisProsthesis DesignRandomized Controlled Trials as TopicRisk FactorsTreatment OutcomeEndoscopic retrograde cholangiopancreatographyPancreatic stent placementPancreatitisPost-endoscopic retrograde cholangiopancreatography pancreatitis

Identifiers

PMID26140006
PMCPMC4481455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.