ArticleThe Indian journal of medical research2015
Sickle cell disease in tribal populations in India.
Article in The Indian journal of medical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
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Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 175 citations in OpenAlex.
- Systematic Review and Meta-analysis on the Prevalence of Common Hemoglobinopathies in India.Annals of African medicine · 2026Pooled it
- A systematic review on hydroxyurea therapy for sickle cell disease in India.The Indian journal of medical research · 2022Pooled it
- Global research trends and influential contributions in sickle cell disease: a bibliometric analysis of the top 100 cited papers.Journal of community genetics · 2026Review
- Review
- α-Thalassemia in Oraons-indigenous tribal population from Jharkhand, India: insights to common deletions.Human genetics · 2026Article
- Sickle Cell Disease: From Ancient Origins to Modern Breakthroughs in Gene Therapy.Biomedicines · 2026Review
- "If People Know, They Will Think Something Is Wrong with Me": An Ethnography of Sickle Cell Hemoglobinopathy, Stigma, and Health Disparities in Tribal Odisha, India.Journal of racial and ethnic health disparities · 2026Article
- Beyond the Diagnosis: Lived Experiences of People with Sickle Cell Disease in South India.Journal of racial and ethnic health disparities · 2026Article
- Efficacy of Ayurveda Regimen as an Adjunct to Hydroxyurea in Sickle Cell Disease: Protocol for a Prospective, Randomized, Open-Label, Blinded End Point Exploratory Study.JMIR research protocols · 2026Article
- Knowledge and Perceptions of the Healthcare Providers Related to Sickle Cell Disease: A Qualitative Study from Chhotaudepur District of Gujarat.Journal of racial and ethnic health disparities · 2026Article
- Haemoglobinopathies and health disparities: findings of a large-scale sample survey among indigenous populations in Odisha, India.BMJ open · 2026Article
- Is sickle cell trait truly benign? A case-control study of physical and mental health outcomes from the sickle cell belt of Eastern India.Journal of community genetics · 2026Article
- India's digital-first approach to sickle cell disease elimination.Archives of public health = Archives belges de sante publique · 2026Article
- Predictors of Acute Chest Syndrome in Patients With Sickle Cell Disease: A Cross-Sectional Observational Study.Cureus · 2026Article
- Health service readiness for implementing the National Sickle Cell Anaemia Elimination Mission in Chamarajanagar District, Karnataka, India: a cross-sectional mixed-methods protocol.BMJ public health · 2026Article
- Article
- Pretest Probability in Ophthalmology: Preserving Diagnostic Calibration While Moving Beyond Race.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- A mixed-methods evaluation to optimize the existing hospital based sickle cell disease care model from a tribal area of Gujarat, India.Journal of public health research · 2026Article
- Efficacy of an Ayurvedic Intervention as an Adjunct to Standard Care in Preventing Acute Pain Crises in Sickle Cell Anemia: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Screening for Hemoglobinopathies: An Inceptive Experience of Centre of Excellence for Sickle Cell Disease.Indian pediatrics · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The sickle gene is widespread among many tribal population groups in India with prevalence of heterozygotes varying from 1-40 per cent. Co-inheritance of the sickle gene with β-thalassaemia, HbD Punjab and glucose-6-phosphate dehydrogenase (G6PD) deficiency has also been reported. Most of the screening programmes in India now use high performance liquid chromatography (HPLC) analysis although the solubility test is also sensitive and cheap. Sickle cell disease (SCD) among tribal populations is generally milder than among non-tribal groups with fewer episodes of painful crises, infections, acute chest syndrome and need for hospitalization. This has partly been attributed to the very high prevalence of α-thalassaemia among these tribes as well as higher foetal haemoglobin levels. However, the clinical presentation is variable with many cases having a severe presentation. There is not much information available on maternal and perinatal outcome in tribal women with sickle cell disease. Newborn screening programmes for SCD have recently been initiated in Maharashtra, Gujarat, Orissa and Chattisgarh and monitoring these birth cohorts will help to understand the natural history of SCD in India. Prenatal diagnosis is acceptable by tribal families in India. The Indian Council of Medical Research and the National Rural Health Mission in different States are undertaking outreach programmes for better management and control of the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.