Evidence map›Paper›PMID 26139589›Full record

ArticleChemical communications (Cambridge, England)2015

PLA2-responsive and SPIO-loaded phospholipid micelles.

Qiang Gao, Lesan Yan, Michael Chiorazzo, E James Delikatny, Andrew Tsourkas, Zhiliang Cheng

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Phospholipase AScience advances · 2021
    Article
  3. Phospholipase AACS nano · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Qiang GaoDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. zcheng@seas.upenn.edu.
Lesan Yan
Michael Chiorazzo
E James Delikatny
Andrew Tsourkas
Zhiliang Cheng
California University of Pennsylvania · USUniversity of Pennsylvania · USIndiana University School of MedicinePhiladelphia University · US

Funding

Tumor-targeted Polymersomes to image and Treat Ovarian CancerR01CA175480 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHENG, ZHILIANG · 2013 to 2017
$1.6M
Highly Paramagnetic, Biodegradable Nanoclusters for Imaging Prostate CancerR01CA157766 · NCI · UNIVERSITY OF PENNSYLVANIA · PI TSOURKAS, ANDREW · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA157766NCI NIH HHS R01CA157766NCI NIH HHS R01 CA175480NCI NIH HHS R01CA175480
6 · The paper itself

Abstract

PLA2-responsive and superparamagnetic iron oxide (SPIO) nanoparticle-loaded phospholipid micelles were developed. The release of a phospholipid-conjugated dye from these micelles was triggered due to phospholipid degradation by phospholipase A2. The high relaxivity of the encapsulated SPIO could enable non-invasive magnetic resonance imaging.

Indexed as

MicellesHumansMagnetite NanoparticlesPhospholipases A2PhospholipidsMagnetite NanoparticlesMicellesPhospholipases A2Phospholipids

Identifiers

PMID26139589
PMCPMC4506235
OpenAlexW1821293095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.