Evidence map›Paper›PMID 26139333›Full record

ReviewCurrent allergy and asthma reports2015

Cutaneous and systemic mastocytosis in children: a risk factor for anaphylaxis?

A Matito, M Carter

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Mediator-Related Symptoms and Anaphylaxis in Children with Mastocytosis.International journal of molecular sciences · 2021
    Review
  6. Review
  7. Pediatric Mastocytosis: Recognition and Management.American journal of clinical dermatology · 2021
    Review
  8. Pediatric Mastocytosis: An Update.Mediterranean journal of hematology and infectious diseases · 2021
    Review
  9. Review
  10. Review
  11. Proposed Diagnostic Algorithm for Patients with Suspected Mast Cell Activation Syndrome.The journal of allergy and clinical immunology. In practice · 2019
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A MatitoInstituto de Estudios de Mastocitosis de Castilla-La Mancha, Hospital Virgen del Valle, Spanish Network on Mastocytosis (REMA), Carretera de Cobisa s/n, 45071, Toledo, Spain, amatito@sescam.jccm.es.
M Carter
Spanish Multiple Sclerosis Network · ES

Funding

Pathogenesis and Treatment of Idiopathic AnaphylaxisZIAAI001092 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CARTER, MELODY C · 2009 to 2025
$10.8M
Intramural NIH HHS
6 · The paper itself

Abstract

Childhood mastocytosis is usually a clonal mast cell disease related to activating mutations in KIT. The symptoms in childhood mastocytosis are typically cutaneous in nature although systemic symptoms including anaphylaxis due to the release of mast cells (MC) mediators can also manifest. The prevalence of anaphylaxis reported in childhood mastocytosis is higher than the rates reported in the pediatric general population, but lower than the prevalence of anaphylaxis described in adult mastocytosis. An extensive cutaneous involvement was reported as a risk factor for anaphylaxis, and patients with diffuse cutaneous mastocytosis have been documented to have more severe anaphylaxis symptoms. Anaphylaxis due to unknown causes or idiopathic anaphylaxis was the primary etiology in pediatric mastocytosis, followed by foods as the most relevant identified trigger; however, hymenoptera stings are not a frequent trigger of anaphylaxis in children with mastocytosis in contrast to the adult patients.

Indexed as

AnaphylaxisAnimalsChildHumansMastocytosis, CutaneousMastocytosis, SystemicPrevalenceRisk Factors

Identifiers

PMID26139333
OpenAlexW865274546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.