ArticleJournal of analytical toxicology2015
Nonsmoker Exposure to Secondhand Cannabis Smoke. III. Oral Fluid and Blood Drug Concentrations and Corresponding Subjective Effects.
Article in Journal of analytical toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Delta-9-tetrahydrocannabinol detection times using mass spectroscopy in oral fluid: a systematic review using a 5 ng/mL cut-off value.International journal of legal medicine · 2026Pooled it
- Household cannabis cessation and adolescent mental health outcomes in a prospective cohort study.BMC medicine · 2026Article
- Field safety and efficacy study with a cannabidiol/cannabidiol acid-rich hemp paste in cats with osteoarthritic pain.Journal of feline medicine and surgery · 2025Article
- Detection of Cannabinoids in Oral Fluid Specimens as the Preferred Biological Matrix for a Point-of-Care Biosensor Diagnostic Device.Biosensors · 2024Review
- Clouding Up Cognition? Secondhand Cannabis and Tobacco Exposure Related to Cognitive Functioning in Youth.Biological psychiatry global open science · 2023Article
- Potential Mechanisms Underlying Marijuana-Associated Periodontal Tissue Destruction.Journal of dental research · 2022Article
- A comprehensive breath test that confirms recent use of inhaled cannabis within the impairment window.Scientific reports · 2021Article
- Occupational Exposure to Secondhand Cannabis Smoke Among Law Enforcement Officers Providing Security at Outdoor Concert Events.Annals of work exposures and health · 2020Article
- Potential for limited reinforcing and abuse-related subjective effects of intranasal oxytocin.Journal of psychopharmacology (Oxford, England) · 2020Article
- Cannabis Use in Pregnant and Breastfeeding Women: Behavioral and Neurobiological Consequences.Frontiers in psychiatry · 2020Review
- Surface Detection of THC Attributable to Vaporizer Use in the Indoor Environment.Scientific reports · 2019Article
- Detection of cannabinoids in hair after cosmetic application of hemp oil.Scientific reports · 2019Article
- Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats.Cannabis and cannabinoid research · 2019Article
- Marijuana-Derived Cannabinoids Trigger a CB2/PI3K Axis of Suppression of the Innate Response to Oral Pathogens.Frontiers in immunology · 2019Article
- Marijuana use in U.S. teen drivers: a comparison of a road-side survey of reported use and fluid tests for tetrahydrocannabinol (THC).Injury epidemiology · 2019Article
- Marijuana and Tobacco Coexposure in Hospitalized Children.Pediatrics · 2018Article
- Trends in Cannabis and Cigarette Use Among Parents With Children at Home: 2002 to 2015.Pediatrics · 2018Article
- Biosignature Discovery for Substance Use Disorders Using Statistical Learning.Trends in molecular medicine · 2018Review
- Health effects of exposure to second- and third-hand marijuana smoke: a systematic review.CMAJ open · 2017Article
- Pediatric Death Due to Myocarditis After Exposure to Cannabis.Clinical practice and cases in emergency medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The increasing use of highly potent strains of cannabis prompted this new evaluation of human toxicology and subjective effects following passive exposure to cannabis smoke. The study was designed to produce extreme cannabis smoke exposure conditions tolerable to drug-free nonsmokers. Six experienced cannabis users smoked cannabis cigarettes [5.3% Δ(9)-tetrahydrocannabinol (THC) in Session 1 and 11.3% THC in Sessions 2 and 3] in a closed chamber. Six nonsmokers were seated alternately with smokers during exposure sessions of 1 h duration. Sessions 1 and 2 were conducted with no ventilation and ventilation was employed in Session 3. Oral fluid, whole blood and subjective effect measures were obtained before and at multiple time points after each session. Oral fluid was analyzed by ELISA (4 ng/mL cutoff concentration) and by LC-MS-MS (limit of quantitation) for THC (1 ng/mL) and total THCCOOH (0.02 ng/mL). Blood was analyzed by LC-MS-MS (0.5 ng/mL) for THC, 11-OH-THC and free THCCOOH. Positive tests for THC in oral fluid and blood were obtained for nonsmokers up to 3 h following exposure. Ratings of subjective effects correlated with the degree of exposure. Subjective effect measures and amounts of THC absorbed by nonsmokers (relative to smokers) indicated that extreme secondhand cannabis smoke exposure mimicked, though to a lesser extent, active cannabis smoking.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.