Evidence map›Paper›PMID 26139050›Full record

ArticleEye (London, England)2015

Trabeculectomy ab interno (trabectome): yet another possibility in the treatment of uncontrolled glaucomatocyclitic crisis under systemic valganciclovir therapy?

M Pahlitzsch, N Torun, J Gonnermann, A K B Maier, U Pleyer, E Bertelmann, A Joussen, M K J Klamann

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. XENGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Observational
  10. Review
  11. Ab interno trabeculectomy: patient selection and perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

M PahlitzschDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
N TorunDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
J GonnermannDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
A K B MaierDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
U PleyerDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
E BertelmannDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
A JoussenDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
M K J KlamannDepartment of ophthalmology, Campus Virchow clinic, Charite University medicine, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the outcome of trabectome surgery in the treatment of glaucomatocyclitic crisis (Posner-Schlossman syndrome) in patients with uncontrolled intraocular pressure (IOP). PATIENTS/

methodsTrabectome surgery was performed in seven patients with diagnosed glaucomatocyclitic crisis and uncontrolled IOP where cytomegalovirus DNA was verified by polymerase chain reaction in aqueous humour samples. All patients were treated with oral valganciclovir. After surgery the patients were followed-up for 12 months.

resultsMean IOP before trabectome surgery was 40±10 mm Hg (range 33-58 mm Hg). The mean number of antiglaucoma medication prior to surgery was 3.1±0.4. By the end of the 12 months, IOP in all patients was reduced to normal level (13±1 mm Hg) and their antiglaucoma medication was decreased to 0.8±1.1. No recurring attack of glaucomatocyclitic crisis occurred. DISCUSSION: In addition to oral valganciclovir therapy, trabectome surgery seems to be a reliable and effective tool for the management of glaucomatocyclitic crisis with uncontrolled IOP.

Indexed as

Administration, OralAdultAgedAntiviral AgentsCombined Modality TherapyCytomegalovirusCytomegalovirus InfectionsDNA, ViralEye Infections, ViralFemaleGanciclovirGlaucomaHumansIntraocular PressureIridocyclitisMaleAntiviral AgentsDNA, ViralGanciclovirValganciclovir

Identifiers

PMID26139050
PMCPMC4815684
OpenAlexW830885092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.