Evidence map›Paper›PMID 26138512›Full record

ArticleBritish journal of clinical pharmacology2015

High metabolic N-oxidation of voriconazole in a patient with refractory aspergillosis and CYP2C19*17/*17 genotype.

Youssef Bennis, Sandra Bodeau, Régis Bouquié, Guillaume Deslandes, Céline Verstuyft, Bérangère Gruson, Michel Andréjak, Anne-Sophie Lemaire-Hurtel, Taieb Chouaki

Registry-linked trialOpen access · bronzeAbstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of clinical pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04727827 (A Prospective Interventional Trial of Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04727827 nacompletednot on this mapstarted 2021, after this paper: background citation

A Prospective Interventional Trial of Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation

TypeinterventionalSponsorWake Forest University Health SciencesRan2021 to 2023Enrolled110ConditionsHematopoietic Cell Transplantation, OncologyArmsPharmacogenomic-guided supportive care
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Youssef BennisLaboratory of pharmacology and toxicology, CHU Amiens Picardie, UPJV, INSERM U1088, France.
Sandra BodeauLaboratory of pharmacology and toxicology, CHU Amiens Picardie, UPJV, INSERM U1088, France.
Régis BouquiéLaboratory of pharmacology and toxicology, Nantes University Hospital, France.
Guillaume DeslandesLaboratory of pharmacology and toxicology, Nantes University Hospital, France.
Céline VerstuyftDepartment of Pharmacology, EA 4123, Le Kremlin Bicêtre University Hospital, Universite Paris Sud, France.
Bérangère GrusonDepartment of Clinical Hematology, CHU Amiens Picardie, France.
Michel AndréjakLaboratory of pharmacology and toxicology, CHU Amiens Picardie, France.
Anne-Sophie Lemaire-HurtelLaboratory of pharmacology and toxicology, CHU Amiens Picardie, France.
Taieb ChouakiLaboratory of mycology, CHU Amiens Picardie, France.
Centre Hospitalier Universitaire Amiens-Picardie · FRNantes Université · FRInserm · FRUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAntifungal AgentsAspergillosisCytochrome P-450 CYP2C19FemaleGenotypeHomozygoteHumansOxidation-ReductionTreatment FailureVoriconazoleAntifungal AgentsCytochrome P-450 CYP2C19Voriconazole

Identifiers

PMID26138512
PMCPMC4594719
OpenAlexW1882246513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.