Evidence map›Paper›PMID 26138329›Full record

ArticleInfection control and hospital epidemiology2015

Reconsidering contact precautions for endemic methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus.

Daniel J Morgan, Rekha Murthy, L Silvia Munoz-Price, Marsha Barnden, Bernard C Camins, B Lynn Johnston, Zachary Rubin, Kaede V Sullivan, Andi L Shane, E Patchen Dellinger and 2 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Infection control and hospital epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03268122 (Comparison of Standard Isolation With Targeted Isolation for Preventing Nosocomial Transmission of MRSA and VRE), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03268122 nacompletednot on this mapstarted 2017, after this paper: background citation

Comparison of Standard Isolation With Targeted Isolation for Preventing Nosocomial Transmission of MRSA and VRE: A Pilot Clinical Trial

TypeinterventionalSponsorVanderbilt University Medical CenterRan2017 to 2018Enrolled1,974ConditionsMRSA, VRE InfectionArmsStandard Contact Isolation, Targeted Contact Isolation
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.

  1. Patient care experience with utilization of isolation precautions: systematic literature review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Contact precautions for MRSA and VRE: where are we now? A survey of theAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024
    Article
  9. Article
  10. Contact precautions for the control of endemic pathogens: Finding the middle path.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Barrier Precautions in the Era of Multidrug Pathogens.Current treatment options in infectious diseases · 2020
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Daniel J Morgan1University of Maryland,Baltimore,Maryland.
Rekha Murthy2Cedars-Sinai Medical Center,Los Angeles,California.
L Silvia Munoz-Price3Medical College of Wisconsin,Milwaukee,Wisconsin.
Marsha Barnden4Adventist Health System,Roseville,California.
Bernard C Camins5University of Alabama at Birmingham,Birmingham,Alabama.
B Lynn Johnston6Dalhousie University,Halifax,Nova Scotia.
Zachary Rubin7David Geffen School of Medicine at UCLA,Los Angeles,California.
Kaede V Sullivan8Clinical Microbiology Laboratory,Children's Hospital of Philadelphia,Philadelphia,Pennsylvania.
Andi L Shane9Emory University School of Medicine,Atlanta,Georgia.
E Patchen Dellinger10Department of Surgery,University of Washington Medical Center,Seattle,Washington.
Mark E Rupp11University of Nebraska Medical Center,Omaha,Nebraska.
Gonzalo Bearman12Medical College of Virginia,Richmond,Virginia.
Cedars-Sinai Medical Center · USDalhousie University · CAEmory University · USMedical College of Wisconsin · USNebraska Medical Center · USUniversity of Alabama at Birmingham · USUniversity of California, Los Angeles · USUniversity of Maryland, Baltimore · USUniversity of Washington · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether contact precautions (CP) are required to control the endemic transmission of methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE) in acute care hospitals is controversial in light of improvements in hand hygiene, MRSA decolonization, environmental cleaning and disinfection, fomite elimination, and chlorhexidine bathing.

objectiveTo provide a framework for decision making around use of CP for endemic MRSA and VRE based on a summary of evidence related to use of CP, including impact on patients and patient care processes, and current practices in use of CP for MRSA and VRE in US hospitals.

designA literature review, a survey of Society for Healthcare Epidemiology of America Research Network members on use of CP, and a detailed examination of the experience of a convenience sample of hospitals not using CP for MRSA or VRE.

participantsHospital epidemiologists and infection prevention experts.

resultsNo high quality data support or reject use of CP for endemic MRSA or VRE. Our survey found more than 90% of responding hospitals currently use CP for MRSA and VRE, but approximately 60% are interested in using CP in a different manner. More than 30 US hospitals do not use CP for control of endemic MRSA or VRE.

conclusionsHigher quality research on the benefits and harms of CP in the control of endemic MRSA and VRE is needed. Until more definitive data are available, the use of CP for endemic MRSA or VRE in acute care hospitals should be guided by local needs and resources.

Indexed as

Methicillin-Resistant Staphylococcus aureusVancomycin-Resistant EnterococciAdultAttitude of Health PersonnelChildCross InfectionGram-Positive Bacterial InfectionsHealth Care SurveysHumansInfection ControlPractice Guidelines as TopicStaphylococcal InfectionsUnited States

Identifiers

PMID26138329
OpenAlexW1889582905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.