ArticleAJNR. American journal of neuroradiology2015
Cytotoxic Edema in Posterior Reversible Encephalopathy Syndrome: Correlation of MRI Features with Serum Albumin Levels.
Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02665598 (Prognostic Observation of Posterior Reversible Encephalopathy Syndrome), which is not on this map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Observation of Posterior Reversible Encephalopathy Syndrome
Who cites it
26 citing papers in PubMed.
- A randomized double-blind placebo-controlled trial of intravenous thiamine for prevention of delirium following allogeneic hematopoietic stem cell transplantation.Journal of psychosomatic research · 2021Trial
- Tacrolimus-induced posterior reversible encephalopathy syndrome following liver transplantation.World journal of transplantation · 2024Article
- Serum albumin and white matter hyperintensities.Research square · 2024Article
- Article
- Article
- Can Post-Operative Posterior Reversible Encephalopathy Syndrome (PRES) Be Considered an Insidious Rare Surgical Complication?Brain sciences · 2023Review
- Advances in imaging findings of preeclampsia-related reversible posterior leukoencephalopathy syndrome.Frontiers in neuroscience · 2023Review
- Factors affecting hospitalization, imaging severity, and complications in posterior reversible encephalopathy syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Uremic encephalopathy: A definite diagnosis by magnetic resonance imaging?European journal of translational myology · 2022Article
- Posterior Reversible Encephalopathy Syndrome: A Review of the Literature.Internal medicine (Tokyo, Japan) · 2022Review
- Cognitive Sequelae of Central-Variant Posterior Reversible Encephalopathy Syndrome (PRES).Case reports in neurological medicine · 2021Article
- Posterior reversible encephalopathy syndrome coexists with acute cerebral infarction: challenges of blood pressure management.Quantitative imaging in medicine and surgery · 2020Article
- Reversible posterior leukoencephalopathy syndrome due to adrenal pheochromocytoma: A case report and literature review.Medicine · 2020Review
- Cerebellar Parieto-occipital Posterior Reversible Encephalopathy Syndrome and Cerebral Metamorphopsia Associated with Asymptomatic Atrial Septum Vegetation and Renal Disease: Case Report.The American journal of case reports · 2020Article
- Posterior Reversible Encephalopathy Syndrome: Clinical Features and Outcome.Frontiers in neurology · 2020Review
- Arginine Vasopressin and Posterior Reversible Encephalopathy Syndrome Pathophysiology: the Missing Link?Molecular neurobiology · 2019Review
- [Posterior reversible encephalopathy syndrome: a case report].The Pan African medical journal · 2019Article
- Delayed Posterior Reversible Leukoencephalopathy Syndrome Triggered by FLOT Chemotherapy.Frontiers in neurology · 2019Article
- Postpartum Posterior Reversible Encephalopathy Syndrome (PRES): Three Case Reports and Literature Review.Case reports in obstetrics and gynecology · 2019Article
- Posterior reversible encephalopathy syndrome with extensive cytotoxic edema after blood transfusion: a case report and literature review.BMC neurology · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposePosterior reversible encephalopathy syndrome is a clinicoradiologic entity with typical MR imaging showing predominant vasogenic and occasional cytotoxic edema. It is unclear whether MR imaging correlates with levels of serum albumin. We determined potential risk factors for development of cytotoxic edema in posterior reversible encephalopathy syndrome. MATERIALS AND
methodsSeventy-nine cases with typical clinical symptoms and characteristic neuroradiologic findings conformed to posterior reversible encephalopathy syndrome diagnostic criteria and were included in this study. FLAIR, DWI, and ADC maps were interpreted to evaluate the severity and type of edema. MR imaging was correlated with the levels of serum albumin, and cytotoxic edema was compared with the location and severity of brain edema.
resultsPure vasogenic edema was found in 53 cases (67.09%), and vasogenic edema complicated with cytotoxic components, in 26 patients (32.91%). There was no difference in serum albumin levels between patients with cytotoxic components and those with vasogenic edema (P = .983). There was a significant difference in the edema scale scores between patients with cytotoxic edema and those with vasogenic edema (P = .006). The percentage of cytotoxic edema located in the area with higher scale scores of edema was significantly larger than that in areas with lower scale scores of edema (P = .002).
conclusionsSerum albumin may contribute to the development of edema in PRES but is not a decisive factor for edema type. Cytotoxic edema in posterior reversible encephalopathy syndrome is probably related to regional decreased perfusion and arteriolopathy. Further work should be undertaken to discover the pathophysiologic mechanisms involved.
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