ReviewJournal of preventive medicine and hygiene2014
Staphylococcus aureus with reduced susceptibility to vancomycin in healthcare settings.
Review in Journal of preventive medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The management of healthcare-related infections through lean methodology: systematic review and meta-analysis of observational studies.Journal of preventive medicine and hygiene · 2022Pooled it
- Prevalence and associated factors of methicillin-resistant and vancomycin-susceptible Staphylococcus aureus among clinical isolates at Hawassa university comprehensive specialized hospital, Ethiopia, 2019-2023.BMC infectious diseases · 2025Article
- Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2025Review
- Green-based anti-biofilm nanoformulations against bacterial contaminations in nosocomial environments.Heliyon · 2025Article
- Exploration the therapeutic effects of sodium houttuyfonate combined with penicillin G on methicillin resistantFrontiers in pharmacology · 2025Article
- Combatting Antibiotic-ResistantJournal of chemical information and modeling · 2024Article
- Article
- Epidemiology and Prevention of Healthcare-Associated Infections in Geriatric Patients: A Narrative Review.International journal of environmental research and public health · 2021Review
- Potential Antimicrobial Activity of Galloyl-Flavonoid Glycosides FromFrontiers in microbiology · 2021Article
- The Prevalence and Determinants of Fusidic Acid Resistance Among Methicillin-ResistantFrontiers in medicine · 2021Article
- Is Post-Reprocessing Microbiological Surveillance of Duodenoscopes Effective in Reducing the Potential Risk in Transmitting Pathogens?International journal of environmental research and public health · 2019Article
- Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus.PLoS pathogens · 2019Article
- Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Children: a Reappraisal of Vancomycin.Current infectious disease reports · 2019Review
- Review
- Epigenetic modulator UVI5008 inhibits MRSA by interfering with bacterial gyrase.Scientific reports · 2018Article
- AJournal of preventive medicine and hygiene · 2018Article
- Multidrug-resistant pattern of food borne illness associated bacteria isolated from cockroaches in meal serving facilities, Jimma, Ethiopia.African health sciences · 2018Article
- Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus.BMC complementary and alternative medicine · 2017Article
- Operating room environment and surgical site infections in arthroplasty procedures.Journal of preventive medicine and hygiene · 2016Article
- Peptides from American alligator plasma are antimicrobial against multi-drug resistant bacterial pathogens including Acinetobacter baumannii.BMC microbiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glycopeptide resistance in Staphylococcus aureus is a source of great concern because, especially in hospitals, this class of antibiotics, particularly vancomycin, is one of the main resources for combating infections caused by methicillin-resistant Staphylococcus aureus strains (MRSA). Reduced susceptibility to vancomycin (VISA) was first described in 1996 in Japan; since then, a phenotype with heterogeneous resistance to vancomycin (h-VISA) has emerged. H-VISA isolates are characterised by the presence of a resistant subpopulation, typically at a rate of 1 in 10(5) organisms, which constitutes the intermediate stage betweenfully vancomycin-susceptible S. aureus (VSSA) and VISA isolates. As VISA phenotypes are almost uniformly cross-resistant to teicoplanin, they are also called Glycopeptides-intermediate Staphylococcus aureus strains (GISA) and, in the case of heterogeneous resistance to glycopeptides, h-GISA. The overall prevalence of h-VISA is low, accounting for approximately 1.3% of all MRSA isolates tested. Mortality due to h-GISA infections is very high (about 70%), especially among patients hospitalised in high-risk departments, such as intensive care units (ICU). Given the great clinical relevance of strains that are heteroresistant to glycopeptides and the possible negative impact on treatment choices, it is important to draw up and implement infection control practices, including surveillance, the appropriate use of isolation precautions, staff training, hand hygiene, environmental cleansing and good antibiotic stewardship.
Indexed as
Identifiers
26137787PMC4718313W1691558826What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.