Evidence map›Paper›PMID 26137416›Full record

ArticleOncoimmunology2015

Consensus nomenclature for CD8

Lionel Apetoh, Mark J Smyth, Charles G Drake, Jean-Pierre Abastado, Ron N Apte, Maha Ayyoub, Jean-Yves Blay, Marc Bonneville, Lisa H Butterfield, Anne Caignard and 49 more

Abstract read
In one paragraph

Article in Oncoimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Merkel cell polyomavirus-specific and CD39Cell reports. Medicine · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Distribution, phenotype, functional and clinical relevance of CD8Cancer immunology, immunotherapy : CII · 2022
    Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

59 authors.

Lionel ApetohINSERM; UMR 866 , Dijon, France ; Centre Georges François Leclerc , Dijon, France ; Université de Bourgogne , Dijon, France.
Mark J SmythQIMR Berghofer Medical Research Institute , Herston, Queensland, Australia.
Charles G DrakeSidney Kimmel Comprehensive Cancer Center; Johns Hopkins University School of Medicine , Baltimore, MD, USA.
Jean-Pierre AbastadoInstitut de Recherches Internationales Servier ; 53, rue Carnot , Suresnes, France.
Ron N ApteThe Shraga Segal Department of Microbiology; Immunology and Genetics ; The Faculty of Health Sciences, Ben Gurion University of the Negev , Beer Sheva, Israel.
Maha AyyoubINSERM, Unité1102; Equipe Labellisée Ligue Contre le Cancer ; Institut de Cancérologie de l'Ouest , Nantes-Saint Herblain; France.
Jean-Yves BlayCancer Research Center of Lyon; INSERM UMR 1052 ; CNRS UMR 5286 , Centre Leon Berard, Lyon, France ; Medical Oncology Department , Lyon, France.
Marc BonnevilleCRCNA, INSERM U892; CNRS UMR 6299 , Nantes, France ; Institut Mérieux , Lyon, France.
Lisa H ButterfieldUniversity of Pittsburgh Cancer Institute, Departments of Medicine, Surgery, and Immunology , Pittsburgh, PA, USA.
Anne CaignardINSERM UMR 1116 , Paris, France.
Chiara CastelliUnit of Immunotherapy of Human Tumor; Department of Experimental Oncology and Molecular Medicine ; Fondazione IRCCS Istituto Nazionale dei Tumori , Milan, Italy.
Federica CavalloDepartment of Molecular Biotechnology and Health Sciences; Molecular Biotechnology Center, University of Torino , Italy.
Esteban CelisCancer Immunology; Inflammation and Tolerance Program; Georgia Regents University Cancer Center ; Augusta, GA, USA.
Lieping ChenDepartment of Immunobiology and Yale Cancer Center; Yale University School of Medicine , New Haven, CT, USA.
Mario P ColomboMolecular Immunology Unit; Department of Experimental Oncology and Molecular Medicine ; Fondazione IRCCS Istituto Nazionale dei Tumori ; Milan, Italy.
Begoña Comin-AnduixUCLA School of Medicine ; Jonsson Comprehensive Cancer Center Los Angeles , CA, USA.
Georges CoukosLudwig Center for Cancer Research; Department of Oncology; University of Lausanne , Switzerland.
Madhav V DhodapkarDepartment of Immunobiology and Yale Cancer Center; Yale University School of Medicine , New Haven, CT, USA.
Glenn DranoffDepartment of Medical Oncology and Cancer Vaccine Center; Dana-Farber Cancer Institute and Department of Medicine ; Brigham and Women's Hospital and Harvard Medical School , Boston, MA, USA.
Ian H FrazerThe University of Queensland , Queensland, Australia.
Wolf-Hervé FridmanCordeliers Research Centre, University of Paris-Descartes , Paris, France.
Dmitry I GabrilovichTranslational Tumor Immunology; The Wistar Institute , Philadelphia, PA, USA.
Eli GilboaDepartment of Microbiology & Immunology; Dodson Interdisciplinary Immunotherapy Institute ; Sylvester Comprehensive Cancer Center; Miller School of Medicine ; University of Miami , Miami, FL, USA.
Sacha GnjaticTisch Cancer Institute; Icahn School of Medicine at Mount Sinai , New York, NY, USA.
Dirk JägerDepartment of Medical Oncology; National Center for Tumor Diseases ; Internal Medicine VI; Heidelberg University Hospital , Heidelberg, Germany.
Pawel KalinskiDepartment of Surgery; University of Pittsburgh ; Pittsburgh, PA, USA.
Howard L KaufmanRutgers Cancer Institute of New Jersey , New Brunswick, NJ, USA.
Rolf KiesslingDepartment of Oncology/Pathology; Karolinska Institutet , Stockholm, Sweden.
John KirkwoodDivision of Hematology/Oncology; Department of Medicine ; School of Medicine; University of Pittsburgh , Pittsburgh; PA; USA ; Melanoma and Skin Cancer Program; University of Pittsburgh Cancer Institute , Pittsburgh, PA, USA.
Alexander KnuthNational Center for Cancer Care & Research , Doha, Qatar.
Roland LiblauINSERM-UMR 1043 ; Toulouse, France ; CNRS ; U5282 , Toulouse, France ; Universite de Toulouse; UPS ; Centre de Physiopathologie Toulouse Purpan (CPTP) ; Toulouse, France ; CHU Toulouse Purpan ; Toulouse, France.
Michael T LotzeHillman Cancer Center; University of Pittsburgh Schools of Health Sciences , Pittsburgh, PA, USA.
Enrico LugliUnit of Clinical and Experimental Immunology; Humanitas Clinical and Research Center , Rozzano, Italy.
Francesco MarincolaResearch Branch; Sidra Medical and Research Centre , Doha, Qatar.
Ignacio MeleroDivision of Oncology; Center for Applied Medical Research and Clinica Universidad de Navarra , Pamploma, Spain.
Cornelis J MeliefLeiden University; ISA Pharmaceuticals , Netherlands.
Thorsten R MempelCenter for Immunology and Inflammatory Diseases; Massachusetts General Hospital ; Harvard Medical School , Boston, MA, USA.
Elizabeth A MittendorfDeparment of Surgical Oncology; University of Texas MD Anderson Cancer Center , Houston, TX, USA.
Kunle OdunDepartments of Gynecologic Oncology and Immunology; Roswell Park Cancer Institute , Buffalo, NY, USA.
Willem W OverwijkDepartment of Melanoma Medical Oncology; University of Texas MD Anderson Cancer Center , Houston, TX, USA.
Anna Karolina PaluckaThe Jackson Laboratory for Genomic Medicine , Farmington, CT, USA.
Giorgio ParmianiDivision of Medical Oncology and Immunotherapy; University Hospital , Siena, Italy.
Antoni RibasUCLA School of Medicine ; Jonsson Comprehensive Cancer Center Los Angeles , CA, USA.
Pedro RomeroLudwig Center for Cancer Research; Department of Oncology; University of Lausanne , Switzerland.
Robert D SchreiberDepartment of Pathology and Immunology; Washington University School of Medicine , St. Louis, MO USA.
Gerold SchulerDepartment of Dermatology; Universitatsklinikum Erlangen , Erlangen, Germany.
Pramod K SrivastavaCenter for Immunotherapy of Cancer and Infectious Diseases; Carole and Ray Neag Comprehensive Cancer Center ; University of Connecticut Health Center , Farmington, CT, USA.
Eric TartourDepartment of Clinical Oncology, INSERM U970; Universite Paris Descartes ; Sorbonne Paris-Cité; Paris ; France; Hôpital Européen Georges Pompidou ; Service d'Immunologie Biologique ; Paris, France.
Danila ValmoriINSERM, Unité1102; Equipe Labellisée Ligue Contre le Cancer ; Institut de Cancérologie de l'Ouest , Nantes-Saint Herblain; France ; Faculty of Medicine, University of Nantes, 44035 Nantes, France.
Sjoerd H van der BurgLeiden University Medical Center , Leiden, Netherlands.
Pierre van der BruggenLudwig Institute for Cancer Research; BrusselsBranch de Duve Institute ; Université Catholique de Louvain , Brussels, Blegium.
Benoît J van den EyndeLudwig Institute for Cancer Research; BrusselsBranch de Duve Institute ; Université Catholique de Louvain , Brussels, Blegium.
Ena WangResearch Branch; Sidra Medical and Research Centre , Doha, Qatar.
Weiping ZouDepartment of Surgery; University of Michigan School of Medicine , Ann Arbor , MI, USA.
Theresa L WhitesideDepartment of Pathology; Immunology, and Otolaryngology ; University of Pittsburgh Cancer Institute , Pittsburgh, PA, USA.
Daniel E SpeiserLudwig Center for Cancer Research; Department of Oncology; University of Lausanne , Switzerland.
Drew M PardollSidney Kimmel Comprehensive Cancer Center; Johns Hopkins University School of Medicine , Baltimore, MD, USA.
Nicholas P RestifoNational Cancer Institute; National Institutes of Health , Bethesda, MD, USA.
Ana C AndersonEvergrande Center for Immunologic Diseases; Ann Romney Center for Neurologic Diseases ; Brigham and Women's Hospital and Harvard Medical School , Boston, MA USA.

Funding

Tumor Microenvironment and MetastasisP30CA010815 · NCI · WISTAR INSTITUTE · PI Luis J Montaner · 1985 to 2026
$75.9M
Building on the success of the adoptive immunotherapy of cancerZIABC010763 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROSENBERG, STEVEN · 2009 to 2020
$25.0M
DEVELOPMENT OF GENOMICS BASED PERSONALIZED CANCER IMMUNOTHERAPYR01CA190700 · NCI · WASHINGTON UNIVERSITY · PI SCHREIBER, ROBERT DAVID · 2015 to 2019
$2.1M
NCI NIH HHS P30 CA010815NCI NIH HHS R01 CA190700
6 · The paper itself

Abstract

Whereas preclinical investigations and clinical studies have established that CD8

Indexed as

anergyanticancer immunityCD8+ T cellscytotoxicityeffectorexhaustionIFNγsenescencestemness

Identifiers

PMID26137416
PMCPMC4485711

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.