Evidence map›Paper›PMID 26137409›Full record

ArticleOncoimmunology2015

An adjuvanted whole cell vaccine as post-remission immunotherapy for acute leukemia.

Robert Weinkove, Lindsay R Ancelet, John D Gibbins, Ian F Hermans

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncoimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Robert WeinkoveMalaghan Institute of Medical Research , Wellington, New Zealand.
Lindsay R AnceletMalaghan Institute of Medical Research , Wellington, New Zealand.
John D GibbinsMalaghan Institute of Medical Research , Wellington, New Zealand ; School of Biological Sciences, Victoria University of Wellington , Wellington, New Zealand.
Ian F HermansMalaghan Institute of Medical Research , Wellington, New Zealand ; School of Biological Sciences, Victoria University of Wellington , Wellington, New Zealand.
Malaghan Institute of Medical Research · NZVictoria University of Wellington · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many acute leukemia patients treated with chemotherapy are at high risk of relapse without allogeneic stem cell transplantation, an immunotherapy that is limited by significant toxicity and donor availability. We propose that post-remission vaccination with a simple autologous whole cell vaccine adjuvanted with α-galactosylceramide may be effective to prevent relapse of acute leukemia.

Indexed as

acute leukemiaimmunotherapyNKT cellα-galactosylceramide

Identifiers

PMID26137409
PMCPMC4485719
OpenAlexW1487244551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.