Evidence map›Paper›PMID 26137387›Full record

ArticleBiomedical optics express2015

Fibre-coupled multiphoton microscope with adaptive motion compensation.

Ben Sherlock, Sean Warren, James Stone, Mark Neil, Carl Paterson, Jonathan Knight, Paul French, Chris Dunsby

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ben SherlockDepartment of Physics, Imperial College London, London, SW7 2AZ, UK.
Sean WarrenDepartment of Physics, Imperial College London, London, SW7 2AZ, UK.
James StoneDepartment of Physics, University of Bath, Bath, BA2 7AY, UK.
Mark NeilDepartment of Physics, Imperial College London, London, SW7 2AZ, UK.
Carl PatersonDepartment of Physics, Imperial College London, London, SW7 2AZ, UK.
Jonathan KnightDepartment of Physics, University of Bath, Bath, BA2 7AY, UK.
Paul FrenchDepartment of Physics, Imperial College London, London, SW7 2AZ, UK.
Chris DunsbyDepartment of Physics, Imperial College London, London, SW7 2AZ, UK ; Centre for Histopathology, Imperial College London, London, SW7 2AZ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the challenge of sample motion during in vivo imaging, we present a fibre-coupled multiphoton microscope with active axial motion compensation. The position of the sample surface is measured using optical coherence tomography and fed back to a piezo actuator that adjusts the axial location of the objective to compensate for sample motion. We characterise the system's performance and demonstrate that it can compensate for axial sample velocities up to 700 µm/s. Finally we illustrate the impact of motion compensation when imaging multiphoton excited autofluorescence in ex vivo mouse skin.

Indexed as

(180.4315) Nonlinear microscopy(330.4150) Motion detection

Identifiers

PMID26137387
PMCPMC4467716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.