ReviewUnited European gastroenterology journal2015
The human gastric microbiota: Is it time to rethink the pathogenesis of stomach diseases?
Review in United European gastroenterology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
118 citing papers in PubMed, 2 syntheses or guidelines pooled it, 250 citations in OpenAlex.
- Gut microbiome alterations during gastric cancer: evidence assessment of case-control studies.Frontiers in microbiology · 2024Pooled it
- Effect ofFrontiers in cellular and infection microbiology · 2022Pooled it
- Article
- Physical, chemical, and structural properties of human gastric organoid-derived mucus.American journal of physiology. Gastrointestinal and liver physiology · 2026Article
- Gastric Microbiota Dysbiosis and Microbiome-Based Interventions in Chronic Atrophic Gastritis.Nutrients · 2026Review
- The gastric ecosystem: assessing resident microbiome vs. transient microorganisms in obesity and following bariatric interventions.NPJ biofilms and microbiomes · 2026Review
- From Laboratory to Real Clinical Practice: A Multidisciplinary Approach Towards the Next Probiotics.Antibiotics (Basel, Switzerland) · 2026Article
- Dietary nitrate drives gastritis by modulating gastric microbiota and metabolites.Cancer biology & medicine · 2026Article
- Species-level dynamics of gastric microbiome after Helicobacter pylori eradication in high-risk Mongolian population.Gut pathogens · 2026Article
- Culturable bacteria in the gastric tissue and diversity of antimicrobial resistance in adults with gastritis.Caspian journal of internal medicine · 2026Article
- The Gut-Heart Axis: A Comprehensive Review of Microbiota's Role in Cardiovascular Health and Disease and Emerging Therapeutic Strategies.Cardiology research and practice · 2026Review
- Microbial Interconnections in One Health: A Critical Nexus Between Companion Animals and Human Microbiomes.Microorganisms · 2025Review
- New perspectives on gastric disorders: the relationship between innate lymphoid cells and microbes in the stomach.Cellular and molecular life sciences : CMLS · 2025Review
- Article
- Intestinal injury and changes of the gut microbiota after ischemic stroke.Frontiers in cellular neuroscience · 2025Review
- Stimulus-responsive biomaterials for Helicobacter pylori eradication.Journal of advanced research · 2024Review
- Microbial composition of gastric lesions: differences based on Helicobacter pylori virulence profile.Scientific reports · 2024Article
- The Effect of Dietary Types on Gut Microbiota Composition and Development of Non-Communicable Diseases: A Narrative Review.Nutrients · 2024Review
- Article
- Exposure to polyethylene microplastics exacerbate inflammatory bowel disease tightly associated with intestinal gut microflora.RSC advances · 2024Review
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough long thought to be a sterile organ, due to its acid production, the human stomach holds a core microbiome.
aimTo provide an update of findings related to gastric microbiota and its link with gastric diseases.
methodsWe conducted a systematic review of the literature.
resultsThe development of culture-independent methods facilitated the identification of many bacteria. Five major phyla have been detected in the stomach: Firmicutes, Bacteroidites, Actinobacteria, Fusobacteria and Proteobacteria. At the genera level, the healthy human stomach is dominated by Prevotella, Streptococcus, Veillonella, Rothia and Haemophilus; however, the composition of the gastric microbiota is dynamic and affected by such factors as diet, drugs and diseases. The interaction between the pre-existing gastric microbiota and Helicobacter pylori infection might influence an individual's risk of gastric disease, including gastric cancer.
conclusionsThe maintenance of bacterial homeostasis could be essential for the stomach's health and highlights the chance for therapeutic interventions targeting the gastric microbiota, even if gastric pH, peristalsis and the mucus layer may prevent bacteria colonization; and the definition of gastric microbiota of the healthy stomach is still an ongoing challenging task.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.