ReviewUnited European gastroenterology journal2015
Use of probe-based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence.
Review in United European gastroenterology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02922049 (Probe-based Confocal Laser Endomicroscopy in Accurate Histopathologic Diagnosis of Neoplastic Gastrointestinal Lesion), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Probe-based Confocal Laser Endomicroscopy in Accurate Histopathologic Diagnosis of Neoplastic Gastrointestinal Lesion
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnitude of Missed Esophageal Adenocarcinoma After Barrett's Esophagus Diagnosis: A Systematic Review and Meta-analysis.Gastroenterology · 2016Pooled it
- Probe-based confocal laser endomicroscopy versus biopsies in the diagnostics of oesophageal and gastric lesions: A prospective, pathologist-blinded study.United European gastroenterology journal · 2020Trial
- Review
- Evaluating the endothelial glycocalyx from bench to bedside: a translational framework for microvascular assessment.Angiogenesis · 2026Review
- Probe-based confocal laser endomicroscopy: progress, challenges, and emerging applications.Surgical endoscopy · 2025Review
- Deep learning-aided optical biopsy achieves whole-chain diagnosis of Correa cascade of gastric cancer: a prospective study.BMC medicine · 2025Article
- Onboard visual micro-servoing on robotic surgery tools.Microsystems & nanoengineering · 2025Article
- Artificial intelligence-aided optical biopsy improves the diagnosis of esophageal squamous neoplasm.World journal of gastroenterology · 2025Article
- Artificial intelligence in advanced endoscopic imaging: transforming optical diagnosis in gastroenterology.Frontiers in medicine · 2025Review
- Advanced endoscopic imaging for detection of Barrett's esophagus.Clinical endoscopy · 2024Review
- Microsurgery Robots: Applications, Design, and Development.Sensors (Basel, Switzerland) · 2023Review
- Current and Future Advances in Surgical Therapy for Pituitary Adenoma.Endocrine reviews · 2023Article
- Unsupervised full-color cellular image reconstruction through disordered optical fiber.Light, science & applications · 2023Article
- Optical Biopsy of Dysplasia in Barrett's Oesophagus Assisted by Artificial Intelligence.Cancers · 2023Article
- [Confocal probe localization algorithm based on region growing and endoscope size prior].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022Article
- The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett's Esophagus and Esophageal Adenocarcinoma.Diagnostics (Basel, Switzerland) · 2022Review
- Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives.World journal of gastrointestinal oncology · 2022Review
- Confocal Laser Endomicroscopy in the Diagnosis of Biliary and Pancreatic Disorders: A Systematic Analysis.Clinical endoscopy · 2022Article
- Classification of the Confocal Microscopy Images of Colorectal Tumor and Inflammatory Colitis Mucosa Tissue Using Deep Learning.Diagnostics (Basel, Switzerland) · 2022Article
- Biliary Tree Diagnostics: Advances in Endoscopic Imaging and Tissue Sampling.Medicina (Kaunas, Lithuania) · 2022Review
Corrections and comments
- Erratum issuedErratum.2015
Authors and funding
26 authors.
Funding
Abstract
backgroundProbe-based confocal laser endomicroscopy (pCLE) provides microscopic imaging during an endoscopic procedure. Its introduction as a standard modality in gastroenterology has brought significant progress in management strategies, affecting many aspects of clinical care and requiring standardisation of practice and training.
objectiveThis study aimed to provide guidance on the standardisation of its practice and training in Barrett's oesophagus, biliary strictures, colorectal lesions and inflammatory bowel diseases.
methodsInitial statements were developed by five group leaders, based on the available clinical evidence. These statements were then voted and edited by the 26 participants, using a modified Delphi approach. After two rounds of votes, statements were validated if the threshold of agreement was higher than 75%.
resultsTwenty-six experts participated and, among a total of 77 statements, 61 were adopted (79%) and 16 were rejected (21%). The adoption of each statement was justified by the grade of evidence.
conclusionpCLE should be used to enhance the diagnostic arsenal in the evaluation of these indications, by providing microscopic information which improves the diagnostic performance of the physician. In order actually to implement this technology in the clinical routine, and to ensure good practice, standardised initial and continuing institutional training programmes should be established.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.