ArticleMalawi medical journal : the journal of Medical Association of Malawi2015
Risk Factors for Neonatal Sepsis and Method for Reduction of Blood Culture Contamination.
Article in Malawi medical journal : the journal of Medical Association of Malawi, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- American Society for Microbiology evidence-based laboratory medicine practice guidelines to reduce blood culture contamination rates: a systematic review and meta-analysis.Clinical microbiology reviews · 2024Pooled it
- Epidemiology, microbiological profile, and antimicrobial resistance patterns of culture-proven neonatal sepsis in a tertiary NICU.BMC pediatrics · 2026Article
- Comparison of risk factors, clinical characteristics, laboratory findings and bacterial etiology between early-onset and late-onset neonatal sepsis in Sana'a City, Yemen.BMC pediatrics · 2025Article
- Characteristics and Associated Risk Factors of Neonatal Sepsis: A Retrospective Study From Saudi Arabia.Cureus · 2024Article
- On prioritising global health's triple crisis of sepsis, COVID-19 and antimicrobial resistance: a mixed-methods study from Malawi.BMC health services research · 2022Article
- Bacteraemia and antibiotic sensitivity in a tertiary neonatal intensive care unit.Southern African journal of infectious diseases · 2021Article
- Cerebral blood flow and serum neuron-specific enolase in early-onset neonatal sepsis.Pediatric research · 2018Observational
- Percentage of Peripheral CD19+CD24hiCD38hi Regulatory B Cells in Neonatal Sepsis Patients and Its Functional Implication.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- The role of MBL2 gene polymorphism in sepsis incidence.International journal of clinical and experimental pathology · 2015Article
- A Quality Improvement Initiative to Reduce Blood Culture Contamination in the Neonatal Unit.Pediatric quality & safetyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFalse-positive blood cultures findings may lead to a falsely increased morbidity and increased hospital costs.
methodThe survey was conducted as retrospective - prospective study and included 239 preterm infants (born before 37 weeks of gestation) who were treated in Neonatal Intensive Care Unit (NICU) in Institute for Child and Youth Health Care of Vojvodina during one year (January 1st, 2012 to December 31st, 2012). The retrospective part of the study focused on examination of incidence of neonatal sepsis and determination of risk factors. In the prospective part of the study infants were sub-divided into two groups: Group 1- infants hospitalized in NICU during the first 6 months of the study; blood cultures were taken by the "clean technique" and checklists for this procedure were not taken. Group 2- neonates hospitalized in NICU during last 6 months of the study; blood cultures were taken by "sterile technique" and checklists for this procedure were taken.
resultsThe main risk factors for sepsis were prelabor rupture of membranes, low gestational age, low birth weight, mechanical ventilation, umbilical venous catheter placement, and abdominal drainage. Staphylococcus aureus and coagulase negative Staphylococcus were the most frequently isolated microorganisms in false-positive blood samples.
conclusionsEducation of employees, use of checklists and sterile sets for blood sampling, permanent control of false positive blood cultures, as well as regular and routine monthly reports are crucial for successful reduction of contamination rates.
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