Evidence map›Paper›PMID 26136906›Full record

ArticleExperimental and therapeutic medicine2015

Protocatechuic acid benefits proliferation and phenotypic maintenance of rabbit articular chondrocytes: An

Like Luo, Qingjun Wei, Lei Liu, Xiao Lin, Cuiwu Lin, L I Zheng, Jinmin Zhao

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Insights into the Action Mechanisms of Traditional Chinese Medicine in Osteoarthritis.Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Like LuoDepartment of Orthopedic Trauma and Hand Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China ; Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Qingjun WeiDepartment of Orthopedic Trauma and Hand Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China ; Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Lei LiuDepartment of Orthopedic Trauma and Hand Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China ; Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Xiao LinSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi 530004, P.R. China ; Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Sciences, Nanning, Guangxi 530022, P.R. China.
Cuiwu LinSchool of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi 530004, P.R. China.
L I ZhengGuangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China ; The Medical and Scientific Research Center, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Jinmin ZhaoDepartment of Orthopedic Trauma and Hand Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China ; Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Guangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous antioxidants exhibit antiarthritic effects due to their inhibitory effect on inflammatory factors. Certain antioxidants, such as protocatechuic acid (PCA) and its analogs, have been reported to be effective in the treatment of arthritis. However, the effect of PCA on chondro-protection may be alleviated due to the induction of apoptosis, as has been demonstrated in stomatocytes. To clearly determine the effect of PCA on the biological and cellular metabolism of rabbit articular chondrocytes

Indexed as

dedifferentiationpolyphenolsprochondrogenic agentproliferationprotocatechuic acidrabbit articular chondrocyte

Identifiers

PMID26136906
PMCPMC4471768
OpenAlexW2090514230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.