ArticleFrontiers in psychology2015
Possible functional links among brain- and skull-related genes selected in modern humans.
Article in Frontiers in psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 63 citations in OpenAlex.
- Natural selection and language genes in humans.Scientific reports · 2026Article
- Delving into the Genetic Causes of Language Impairment in a Case of Partial Deletion ofMolecular syndromology · 2023Article
- Review
- Reply to: "Historical pursuits of the language pathway hypothesis of schizophrenia".NPJ schizophrenia · 2021Article
- PolyQ length co-evolution in neural proteins.NAR genomics and bioinformatics · 2021Article
- The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia.NPJ schizophrenia · 2021Article
- Language Impairment with a Partial Duplication ofMolecular syndromology · 2020Article
- Robust Candidates for Language Development and Evolution Are Significantly Dysregulated in the Blood of People With Williams Syndrome.Frontiers in neuroscience · 2019Article
- No Country for Oldowan Men: Emerging Factors in Language Evolution.Frontiers in psychology · 2019Review
- Williams Syndrome, Human Self-Domestication, and Language Evolution.Frontiers in psychology · 2019Article
- Ectopic expression of the osteogenic master geneWorld journal of stem cells · 2018Article
- Language and Cognitive Impairment Associated with a Novel p.Cys63Arg Change in the MED13L Transcriptional Regulator.Molecular syndromology · 2018Article
- Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication Syndrome.Frontiers in pediatrics · 2018Article
- Toward the Language Oscillogenome.Frontiers in psychology · 2018Article
- The language-ready head: Evolutionary considerations.Psychonomic bulletin & review · 2017Review
- Language Impairment Resulting from a de novo Deletion of 7q32.1q33.Molecular syndromology · 2016Article
- The Oscillopathic Nature of Language Deficits in Autism: From Genes to Language Evolution.Frontiers in human neuroscience · 2016Article
- Language Impairments in ASD Resulting from a Failed Domestication of the Human Brain.Frontiers in neuroscience · 2016Article
- Bridging the Gap between Genes and Language Deficits in Schizophrenia: An Oscillopathic Approach.Frontiers in human neuroscience · 2016Article
- Implications of Oxytocin in Human Linguistic Cognition: From Genome to Phenome.Frontiers in neuroscience · 2016Article
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Authors and funding
2 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The sequencing of the genomes from extinct hominins has revealed that changes in some brain-related genes have been selected after the split between anatomically-modern humans and Neanderthals/Denisovans. To date, no coherent view of these changes has been provided. Following a line of research we initiated in Boeckx and Benítez-Burraco (2014a), we hypothesize functional links among most of these genes and their products, based on the existing literature for each of the gene discussed. The genes we focus on are found mutated in different cognitive disorders affecting modern populations and their products are involved in skull and brain morphology, and neural connectivity. If our hypothesis turns out to be on the right track, it means that the changes affecting most of these proteins resulted in a more globular brain and ultimately brought about modern cognition, with its characteristic generativity and capacity to form and exploit cross-modular concepts, properties most clearly manifested in language.
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