Evidence map›Paper›PMID 26136628›Full record

ArticleJournal of the Saudi Heart Association2015

The platelet-to-lymphocyte ratio as a predictor of all-cause mortality in patients with coronary artery disease undergoing elective percutaneous coronary intervention and stent implantation.

Tadeusz Osadnik, Jarosław Wasilewski, Andrzej Lekston, Joanna Strzelczyk, Anna Kurek, Małgorzata Gonera, Marcin Gawlita, Rafał Reguła, Kamil Bujak, Bożena Szyguła-Jurkiewicz and 2 more

Abstract read
In one paragraph

Article in Journal of the Saudi Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Evaluation of peripheral blood inflammatory biomarkers in sickle cell disease with and without retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tadeusz OsadnikMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Jarosław WasilewskiMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Andrzej LekstonMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Joanna StrzelczykMedical University of Silesia, School of Medicine with the Division of Dentistry, Department of Medical Biology, Zabrze, Poland.
Anna KurekMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Małgorzata GoneraMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Marcin GawlitaMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Rafał RegułaMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Kamil BujakMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Bożena Szyguła-JurkiewiczMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.
Andrzej WiczkowskiMedical University of Silesia, School of Medicine with the Division of Dentistry, Department of Medical Biology, Zabrze, Poland.
Lech PolońskiMedical University of Silesia, School of Medicine with the Division of Dentistry, IIIrd Chair and Department of Cardiology, Silesian Centre for Heart Diseases, Zabrze, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is no data regarding the association between the platelet-to-lymphocyte ratio (PLR) and long-term mortality in patients with stable coronary artery disease (SCAD). The aim of this study is to evaluate the utility of the pre-procedural PLR for predicting long-term, all-cause mortality in patients with SCAD undergoing percutaneous coronary intervention (PCI) and stent implantation.

methodsWe analyzed a total of 2959 consecutive patients with SCAD who underwent PCI (balloon angioplasty followed by stent implantation or direct stenting) between July 2006 and December 2011 at our institution. The patients were stratified into tertiles according to their admission PLR. The association between the PLR value and the outcomes was assessed using Cox proportional regression analysis after adjusting for clinical angiographic and laboratory data.

resultsDuring median follow-up of 1124 days, mortality was highest in patients with PLR within the 3rd tertile as compared to the 2nd and the 1st tertile (11.0% vs 8.7% vs. 9.6%, respectively, p = 0.03). PLR remained associated with mortality in multivariable analysis including clinical variables, ejection fraction and angiographic parameters HR (per 10 units increase) = 1.02 [95%CI,1.01 ÷ 1.04, p = 0.006]. After adjustment for the eGFR and hemoglobin levels, PLR was however no longer significantly associated with mortality.

conclusionPLR has potential predictive value in patients with SCAD, which has not been reported previously, but statistical significance disappears after adjusting for estimated glomerular filtration rate (eGFR) and hemoglobin levels as a potential confounding variable.

Indexed as

MortalityPercutaneous coronary interventionPlatelet-to-lymphocyte ratio

Identifiers

PMID26136628
PMCPMC4481420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.