Evidence map›Paper›PMID 26136621›Full record

ArticleInvertebrate reproduction & development2015

Exploring the physiology and pathology of aging in the intestine of

Heinrich Jasper

Abstract read
In one paragraph

Article in Invertebrate reproduction & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Glucomannan Hydrolysate Promotes Gut Proliferative Homeostasis and Extends Life Span in Drosophila melanogaster.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
  14. Article
  15. On the Fly: Recent Progress on Autophagy and Aging in Drosophila.Frontiers in cell and developmental biology · 2019
    Review
  16. Article
  17. International journal of molecular sciences · 2018
    Review
  18. Mutations of mitochondrial DNA are not major contributors to aging of fruit flies.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Heinrich JasperBuck Institute for Research on Aging , 8001 Redwood Boulevard, Novato , CA 94945-1400 , USA.

Funding

Regulation of UV-Induced ApoptosisR01EY018177 · NEI · UNIVERSITY OF ROCHESTER · PI JASPER, HEINRICH · 2008 to 2018
$3.1M
Systemic coordination of stress responses by insulin signalingR01AG028127 · NIA · UNIVERSITY OF ROCHESTER · PI JASPER, HEINRICH · 2006 to 2015
$3.0M
Redox Signaling and Stem Cell FunctionR01GM100196 · NIGMS · UNIVERSITY OF ROCHESTER · PI BOHMANN, DIRK, JASPER, HEINRICH · 2012 to 2015
$1.7M
NEI NIH HHS R01 EY018177NIA NIH HHS R01 AG028127NIGMS NIH HHS R01 GM100196
6 · The paper itself

Abstract

The gastrointestinal tract, due to its role as a digestive organ and as a barrier between the exterior and interior milieus, is critically impacted by dietary, environmental, and inflammatory conditions that influence health and lifespan. Work in flies is now uncovering the multifaceted molecular mechanisms that control homeostasis in this tissue, and establishing its central role in health and lifespan of metazoans. The

Indexed as

agingDrosophila melanogasterintestinal homeostasisregeneration

Identifiers

PMID26136621
PMCPMC4463993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.