Evidence map›Paper›PMID 26136620›Full record

ArticleInvertebrate reproduction & development2015

Aging in the colonial chordate,

Roma Munday, Delany Rodriguez, Alessandro Di Maio, Susannah Kassmer, Brian Braden, Daryl A Taketa, Adam Langenbacher, Anthony De Tomaso

Open access · bronzeAbstract read
In one paragraph

Article in Invertebrate reproduction & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. The Onset of Whole-Body Regeneration inFrontiers in cell and developmental biology · 2022
    Article
  2. Vascular Aging in the Invertebrate Chordate,Frontiers in molecular biosciences · 2021
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Roma MundayDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Delany RodriguezDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Alessandro Di MaioDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Susannah KassmerDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Brian BradenDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Daryl A TaketaDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Adam LangenbacherDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
Anthony De TomasoDepartment of Molecular, Cellular and Developmental Biology, UC Santa Barbara , Santa Barbara , CA 93106 , USA.
University of California, Santa Barbara · US

Funding

Molecular Mechanisms of Protochordate AllorecognitionR01AI041588 · NIAID · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI DE TOMASO, ANTHONY W · 1998 to 2014
$4.6M
Aging and Regeneration in a basal chordateR01AG037966 · NIA · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI DE TOMASO, ANTHONY W · 2010 to 2014
$1.6M
NIAID NIH HHS R01 AI041588NIA NIH HHS R01 AG037966
6 · The paper itself

Abstract

What mechanisms underlie aging? One theory, the wear-and-tear model, attributes aging to progressive deterioration in the molecular and cellular machinery which eventually lead to death through the disruption of physiological homeostasis. The second suggests that life span is genetically programmed, and aging may be derived from intrinsic processes which enforce a non-random, terminal time interval for the survivability of the organism. We are studying an organism that demonstrates both properties: the colonial ascidian,

Indexed as

agingregenerationstem cellstunicate

Identifiers

PMID26136620
PMCPMC4463770
OpenAlexW2058490859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.