Evidence map›Paper›PMID 26136590›Full record

ArticleThe Journal of nutrition2015

Milk Consumption after Age 9 Years Does Not Predict Age at Menarche.

Jenny L Carwile, Walter C Willett, Molin Wang, Janet Rich-Edwards, A Lindsay Frazier, Karin B Michels

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jenny L CarwileDepartments of Epidemiology.
Walter C WillettDepartments of Epidemiology, Nutrition, and Channing Division of Network Medicine, Department of Medicine, and.
Molin WangBiostatistics, Harvard T.H. Chan School of Public Health, Boston, MA;
Janet Rich-EdwardsDepartments of Epidemiology, Channing Division of Network Medicine, Department of Medicine, and Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA; and.
A Lindsay FrazierChanning Division of Network Medicine, Department of Medicine, and Department of Pediatric Oncology, Dana-Farber/Children's Hospital Cancer Center, Boston, MA.
Karin B MichelsDepartments of Epidemiology, Channing Division of Network Medicine, Department of Medicine, and Obstetrics and Gynecology Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; kmichels@research.bwh.harvard.edu.
Harvard University · USBrigham and Women's Hospital · US

Funding

Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Predictors of Mammary Gland Development & Breast Fibroglandular Volume at pubertyR01CA158313 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MICHELS, KARIN B · 2012 to 2015
$1.9M
Predoctoral Training Program in Reproductive, Perinatal & Pediatric EpidemiologyT32HD060454 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI MICHELS, KARIN B · 2010 to 2014
$1.1M
Adolescent Dietary Pattern and Premenopausal Breast CancerR03CA170952 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHELS, KARIN B · 2013 to 2014
$174k
Predictors of MenarcheR03CA106238 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRAZIER, LINDSAY A · 2003 to 2004
$129k
NCI NIH HHS R01CA158313NCI NIH HHS R03 CA 106238NCI NIH HHS R03CA170952NICHD NIH HHS T32HD060454NIEHS NIH HHS T32ES007069
6 · The paper itself

Abstract

backgroundRegular milk consumption during childhood and adolescence is recommended for bone health. However, milk consumption increases circulating insulin-like growth factor I concentrations, and may also accelerate puberty.

objectiveWe prospectively investigated the association between milk consumption and age at menarche in the Growing Up Today Study.

methodsStudy participants were 5583 US girls who were premenarcheal and ages 9-14 y in 1996. Girls were followed through 2001, at which time 97% of noncensored participants had reported menarche. Frequency of milk and meat consumption was calculated with the use of annual youth/adolescent food frequency questionnaires from 1996-1998. Intake of related nutrients was also measured. Age at menarche was self-reported annually through 2001.

resultsDuring follow-up, 5227 girls attained menarche over 10,555 accrued person-years. In models adjusted for dietary and sociodemographic predictors of menarche, frequency of milk consumption did not predict age at onset of menarche (for >3 glasses of milk/d vs. 1.1-4 glasses/wk, HR: 0.93; 95% CI: 0.83, 1.04). After additional adjustment for body size, premenarcheal girls consuming >3 glasses of milk daily were 13% less likely (95% CI: -3%, -23%; P-trend: <0.01) to attain menarche in the next month relative to those consuming 1.1-4 glasses/wk. Neither total meat nor red meat consumption was associated with age at menarche.

conclusionsOur findings suggest that regular consumption of milk in girls aged ≥9 y is unlikely to substantially affect age at onset of menarche. Studies assessing associations between diet in early childhood and pubertal timing may be more illuminating.

Indexed as

DietMilkAdolescentAnimalsChildEnergy IntakeFeeding BehaviorFemaleHumansMeatMenarcheProportional Hazards ModelsUnited Statesdairy productsdietGrowing Up Today Studymeatmenarchemilk

Identifiers

PMID26136590
PMCPMC4516774
OpenAlexW2215073594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.