Evidence map›Paper›PMID 26136555›Full record

ReviewAmerican journal of physiology. Renal physiology2015

Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron.

Donghai Wen, Steven C Sansom

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of physiology. Renal physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Maintaining KAmerican journal of physiology. Renal physiology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donghai WenDepartment of Cellular/Integrative Physiology, University of Nebraska Medical Center, Omaha, Nebraska donghai.wen@phhs.org.
Steven C SansomDepartment of Cellular/Integrative Physiology, University of Nebraska Medical Center, Omaha, Nebraska.
University of Nebraska Medical Center · US

Funding

Role of BK-Beta 1 in flow-dependent K+ secretion in the CNTR01DK071014 · NIDDK · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SANSOM, STEVEN · 2007 to 2015
$2.7M
Role of BK-alpha/beta 4 in renal secretionR01DK092474 · NIDDK · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SANSOM, STEVEN · 2011 to 2015
$1.6M
NIDDK NIH HHS R01 DK071014NIDDK NIH HHS R01 DK092474
6 · The paper itself

Abstract

The electrogenic Na(+)-HCO3 (-) cotransporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid-base, and K(+) and Ca(2+) transport in the distal nephron.

Indexed as

AnimalsBiological TransportElectrolytesHumansHypertension, RenalKidneyNephronsSodium-Bicarbonate SymportersWater-Electrolyte BalanceElectrolytesSodium-Bicarbonate Symportersacid-baseCa2+hypertensionK+NBCe2

Identifiers

PMID26136555
PMCPMC6189740
OpenAlexW2340911411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.