ArticleJournal of experimental botany2015
Brassinazole resistant 1 (BZR1)-dependent brassinosteroid signalling pathway leads to ectopic activation of quiescent cell division and suppresses columella stem cell differentiation.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Article
- ROS-mediated interplay between brassinosteroids and gibberellic acids antagonistically modulates asymmetric periclinal cell division leading to middle cortex formation inPlant signaling & behavior · 2025Article
- Out of the Niche: A Bird's-Eye View of the Molecular Networks Controlling Root Stem Cells.Plants (Basel, Switzerland) · 2025Review
- To grow or not to grow: the enigma of plant root growth dynamism.Plant molecular biology · 2025Review
- BZR1 promotes pluripotency acquisition and callus development through direct regulation of ARF7 and ARF19.EMBO reports · 2025Article
- Crosstalk among plant hormone regulates the root development.Plant signaling & behavior · 2024Review
- Redox regulation of meristem quiescence: outside/in.Journal of experimental botany · 2024Review
- Multi-scale mechanisms driving root regeneration: From regeneration competence to tissue repatterning.The Plant journal : for cell and molecular biology · 2024Review
- PfPIN5 promotes style elongation by regulating cell length in Primula forbesii Franch.Annals of botany · 2024Article
- BZR1 and BES1 transcription factors mediate brassinosteroid control over root system architecture in response to nitrogen availability.Frontiers in plant science · 2024Article
- Recent Updates on ALMT Transporters' Physiology, Regulation, and Molecular Evolution in Plants.Plants (Basel, Switzerland) · 2023Review
- Asymmetric cell division in plant development.Journal of integrative plant biology · 2023Review
- Inhibition of the Glycogen Synthase Kinase 3 Family by the Bikinin Alleviates the Long-Term Effects of Salinity in Barley.International journal of molecular sciences · 2022Article
- Salicylic Acid in Root Growth and Development.International journal of molecular sciences · 2022Review
- Article
- Regulation of tomato fruit elongation by transcription factor BZR1.7 through promotion ofHorticulture research · 2022Article
- Brassinazole Resistant 1 Activity Is Organ-Specific and Genotype-Dependent in Barley Seedlings.International journal of molecular sciences · 2021Article
- Root-System Architectures of Two Cuban Rice Cultivars with Salt Stress at Early Development Stages.Plants (Basel, Switzerland) · 2021Article
- Integrative Roles of Phytohormones on Cell Proliferation, Elongation and Differentiation in theFrontiers in plant science · 2021Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous publications have shown that BRI1 EMS suppressor 1 (BES1), a positive regulator of the brassinosteroid (BR) signalling pathway, enhances cell divisions in the quiescent centre (QC) and stimulates columella stem cell differentiation. Here, it is demonstrated that BZR1, a BES1 homologue, also promotes cell divisions in the QC, but it suppresses columella stem cell differentiation, opposite to the action of BES1. In addition, BR and its BZR1-mediated signalling pathway are shown to alter the expression/subcellular distribution of pin-formed (PINs), which may result in changes in auxin movement. BR promotes intense nuclear accumulation of BZR1 in the root tip area, and the binding of BZR1 to the promoters of several root development-regulating genes, modulating their expression in the root stem cell niche area. These BZR1-mediated signalling cascades may account for both the ectopic activation of QC cell divisions as well as the suppression of the columella stem cell differentiation. They could also inhibit auxin-dependent distal stem cell differentiation by antagonizing the auxin/WOX5-dependent pathway. In conclusion, BZR1-/BES1-mediated BR signalling pathways show differential effects on the maintenance of root apical meristem activities: they stimulate ectopic QC division while they show opposite effects on the differentiation of distal columella stem cells in a BR concentration- and BZR1-/BES1-dependent manner.
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