ArticleJournal of experimental botany2015
Mitogen-activated protein kinase kinase 5 (MKK5)-mediated signalling cascade regulates expression of iron superoxide dismutase gene in Arabidopsis under salinity stress.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.
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37 citing papers in PubMed, 87 citations in OpenAlex.
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- Identification and analysis of MAPK cascade gene families of Camellia oleifera and their roles in response to cold stress.Molecular biology reports · 2024Article
- Comprehensive analysis of MAPK gene family in upland cotton (Gossypium hirsutum) and functional characterization of GhMPK31 in regulating defense response to insect infestation.Plant cell reports · 2024Article
- Transcriptome Expression Profiling Reveals the Molecular Response to Salt Stress inPlants (Basel, Switzerland) · 2024Article
- Phosphoproteome analyses pinpoint the F-box protein SLOW MOTION as a regulator of warm temperature-mediated hypocotyl growth in Arabidopsis.The New phytologist · 2024Article
- Inducing salt stress tolerance in bitter gourd (Frontiers in plant science · 2024Article
- Transcriptomics and physiology reveal the mechanism of potassium indole-3-butyrate (IBAK) mediating rice resistance to salt stress.BMC plant biology · 2023Article
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- GmMPK6 Positively Regulates Salt Tolerance through Induction ofAntioxidants (Basel, Switzerland) · 2023Article
- Harnessing the role of mitogen-activated protein kinases against abiotic stresses in plants.Frontiers in plant science · 2023Review
- Dimethylthiourea Alleviates Drought Stress by Suppressing Hydrogen Peroxide-Dependent Abscisic Acid-Mediated Oxidative Responses in an Antagonistic Interaction with Salicylic Acid inAntioxidants (Basel, Switzerland) · 2022Article
- Crystal structure of the phosphorylatedActa biochimica et biophysica Sinica · 2022Article
- The ABCISIC ACID INSENSITIVE (ABI) 4 Transcription Factor Is Stabilized by Stress, ABA and Phosphorylation.Plants (Basel, Switzerland) · 2022Article
- Mitogen-Activated Protein Kinase Is Involved in Salt Stress Response in Tomato (International journal of molecular sciences · 2022Article
- Functional analysis of mitogen-activated protein kinases (MAPKs) in potato under biotic and abiotic stress.Molecular breeding : new strategies in plant improvement · 2022Review
- Reactive Oxygen Species in Plants: From Source to Sink.Antioxidants (Basel, Switzerland) · 2022Review
- Article
- Plant Mitogen-Activated Protein Kinase Cascades in Environmental Stresses.International journal of molecular sciences · 2021Review
Corrections and comments
- Erratum issued
- Erratum issuedCorrection.2022
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Superoxide dismutases (SODs) are involved in plant adaptive responses to biotic and abiotic stresses but the upstream signalling process that modulates their expression is not clear. Expression of two iron SODs, FSD2 and FSD3, was significantly increased in Arabidopsis in response to NaCl treatment but blocked in transgenic MKK5-RNAi plant, mkk5. Using an assay system for transient expression in protoplasts, it was found that mitogen-activated protein kinase kinase 5 (MKK5) was also activated in response to salt stress. Overexpression of MKK5 in wild-type plants enhanced their tolerance to salt treatments, while mkk5 mutant exhibited hypersensitivity to salt stress in germination on salt-containing media. Moreover, another kinase, MPK6, was also involved in the MKK5-mediated iron superoxide dismutase (FSD) signalling pathway in salt stress. The kinase activity of MPK6 was totally turned off in mkk5, whereas the activity of MPK3 was only partially blocked. MKK5 interacted with the MEKK1 protein that was also involved in the salt-induced FSD signalling pathway. These data suggest that salt-induced FSD2 and FSD3 expressions are influenced by MEKK1 via MKK5-MPK6-coupled signalling. This MAP kinase cascade (MEKK1, MKK5, and MPK6) mediates the salt-induced expression of iron superoxide dismutases.
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