Evidence map›Paper›PMID 26135946›Full record

ArticleScientific reports2015

Cortisol and testosterone increase financial risk taking and may destabilize markets.

Carlos Cueva, R Edward Roberts, Tom Spencer, Nisha Rani, Michelle Tempest, Philippe N Tobler, Joe Herbert, Aldo Rustichini

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Investigating the effects of single-dose intranasal testosterone on economic preferences in a large randomized trial of men.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Trial
  3. Opposing Roles of Testosterone and Cortisol in Prosocial Risk-Taking.Behavioral sciences (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Mortality and morbidity in ageing men: Biology, Lifestyle and Environment.Reviews in endocrine & metabolic disorders · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Testosterone, Cortisol and Financial Risk-Taking.Frontiers in behavioral neuroscience · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Carlos CuevaDepartamento de Fundamentos del Análisis Económico, Universidad de Alicante, Spain.
R Edward RobertsDivision of Brain Sciences, Department of Medicine, Imperial College London, UK.
Tom Spencer1] Department of Psychiatry, University of Cambridge, UK [2] Cambridgeshire and Peterborough NHS Foundation Trust, Elizabeth House, Fulbourn Hospital, Cambridge, UK.
Nisha RaniCambridgeshire and Peterborough NHS Foundation Trust, Elizabeth House, Fulbourn Hospital, Cambridge, UK.
Michelle TempestRoyal College of Psychiatrists, UK.
Philippe N ToblerLaboratory for Social and Neural Systems Research, Department of Economics, University of Zurich, Switzerland.
Joe HerbertJohn van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, UK.
Aldo Rustichini1] Department of Economics, University of Minnesota, USA [2] Department of Physiology, Development and Neuroscience, University of Cambridge, UK.
Fulbourn Hospital · GBImperial College London · GBLaboratory for Social and Neural Systems Research · CHRoyal College of Psychiatrists · GBUniversity of Alicante · ESUniversity of Cambridge · GBUniversity of Minnesota · US

Funding

Medical Research Council Mr/J004685/1Medical Research Council MR/J004685/1
6 · The paper itself

Abstract

It is widely known that financial markets can become dangerously unstable, yet it is unclear why. Recent research has highlighted the possibility that endogenous hormones, in particular testosterone and cortisol, may critically influence traders' financial decision making. Here we show that cortisol, a hormone that modulates the response to physical or psychological stress, predicts instability in financial markets. Specifically, we recorded salivary levels of cortisol and testosterone in people participating in an experimental asset market (N = 142) and found that individual and aggregate levels of endogenous cortisol predict subsequent risk-taking and price instability. We then administered either cortisol (single oral dose of 100 mg hydrocortisone, N = 34) or testosterone (three doses of 10 g transdermal 1% testosterone gel over 48 hours, N = 41) to young males before they played an asset trading game. We found that both cortisol and testosterone shifted investment towards riskier assets. Cortisol appears to affect risk preferences directly, whereas testosterone operates by inducing increased optimism about future price changes. Our results suggest that changes in both cortisol and testosterone could play a destabilizing role in financial markets through increased risk taking behaviour, acting via different behavioural pathways.

Indexed as

Decision MakingInvestmentsAdolescentAdultFemaleGames, ExperimentalHumansHydrocortisoneMaleRisk-TakingSalivaTestosteroneYoung AdultHydrocortisoneTestosterone

Identifiers

PMID26135946
PMCPMC4489095
OpenAlexW905992588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.