ArticleScientific reports2015
External control of reactions in microdroplets.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Study on Microdroplets Generation and Detection Method in Four-Way Microfluid Structure (FWMS) by Double Photoresist Method Pulses.Micromachines · 2025Article
- Water-in-water droplet microfluidics: A design manual.Biomicrofluidics · 2022Review
- Microfluidic harvesting of breast cancer tumor spheroid-derived extracellular vesicles from immobilized microgels for single-vesicle analysis.Lab on a chip · 2022Article
- pH-Triggered Assembly of Endomembrane Multicompartments in Synthetic Cells.ACS synthetic biology · 2022Article
- Molecular reactions at aqueous interfaces.Nature reviews. Chemistry · 2020Review
- Monitoring and external control of pH in microfluidic droplets during microbial culturing.Microbial cell factories · 2020Article
- Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics.Nature materials · 2018Article
- Viral fusion efficacy of specific H3N2 influenza virus reassortant combinations at single-particle level.Scientific reports · 2016Article
- Droplet microfluidics for kinetic studies of viral fusion.Biomicrofluidics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scale reduction of chemical reactions enables novel screening and synthesis approaches that facilitate a highly parallelized and combinatorial exploration of chemical space. Droplet-based microfluidics have evolved as a powerful platform to allow many chemical reactions within small volumes that each can be controlled and manipulated. A significant technical challenge is the ability to change the concentration of reactants inside a droplet. Here we describe a strategy that relies on the use of reactants that are soluble in both oil and water and allow a passive, diffusive exchange of reactants between the oil and aqueous phases to externally control composition of the droplets. We demonstrate the applicability of our approach by externally changing the pH inside microdroplets without the need for physical manipulation or droplet merging.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.