Evidence map›Paper›PMID 26135596›Full record

ReviewCNS spectrums2015

Cognitive remediation: potential novel brain-based treatment for bipolar disorder in children and adolescents.

Daniel P Dickstein, Grace K Cushman, Kerri L Kim, Alexandra B Weissman, Ezra Wegbreit

Open access · greenAbstract readReview
In one paragraph

Review in CNS spectrums, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cognitive Flexibility and Impulsivity Deficits in Suicidal Adolescents.Research on child and adolescent psychopathology · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Irritability in Youths: A Translational Model.The American journal of psychiatry · 2017
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel P Dickstein
Grace K Cushman
Kerri L Kim
Alexandra B Weissman
Ezra Wegbreit
Bradley Hospital · USBrown University · US

Funding

RESEARCH TRAINING IN CHILD MENTAL HEALTHT32MH019927 · NIMH · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI Kristen G Benito, Anthony Spirito · 1994 to 2026
$7.8M
Bio-Behavioral Markers of Bipolar ConversionR01MH087513 · NIMH · BROWN UNIVERSITY · PI DICKSTEIN, DANIEL P · 2009 to 2013
$1.8M
COGFLEX: Pilot Translational Intervention for Pediatric Bipolar DisorderR33MH096850 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI DICKSTEIN, DANIEL P · 2014 to 2016
$670k
COGFLEX: Pilot Translational Intervention for Pediatric Bipolar DisorderR21MH096850 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI DICKSTEIN, DANIEL P · 2012 to 2013
$406k
NIMH NIH HHS 5R01MH087513NIMH NIH HHS 5R21MH096850NIMH NIH HHS R01 MH087513NIMH NIH HHS R21 MH096850NIMH NIH HHS R33 MH096850NIMH NIH HHS T32 MH019927
6 · The paper itself

Abstract

Bipolar disorder (BD) is among the most impairing psychiatric disorders affecting children and adolescents, despite our best psychopharmacological and psychotherapeutic treatments. Cognitive remediation, defined as a behavioral intervention designed to improve cognitive functions so as to reduce psychiatric illness, is an emerging brain-based treatment approach that has thus far not been studied in pediatric BD. The present article reviews the basic principles of cognitive remediation, describes what is known about cognitive remediation in psychiatric disorders, and delineates potential brain/behavior alterations implicated in pediatric BD that might be targets for cognitive remediation. Emerging data show that cognitive remediation may be useful in children and adults with schizophrenia, ADHD, and anxiety disorders, and in adults with BD. Potential targets for cognitive remediation in pediatric BD include face processing, response inhibition, frustration, and cognitive flexibility. Further study is warranted to determine if cognitive remediation for these targets, or others, may serve as a novel, brain-based treatment for pediatric BD.

Indexed as

CognitionAdolescentBehavior TherapyBipolar DisorderBrainChildHumans

Identifiers

PMID26135596
PMCPMC4722947
OpenAlexW2165145052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.