ArticlePLoS neglected tropical diseases2015
Echinococcosis: An Economic Evaluation of a Veterinary Public Health Intervention in Rural Canada.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Worldwide literature on epidemiology of human alveolar echinococcosis: a systematic review of research published in the twenty-first century.Infection · 2019Pooled it
- Trends in the global burden of cystic echinococcosis among children and adolescents from 1990 to 2021: An analysis based on the Global Burden of Disease Study 2021.PLoS neglected tropical diseases · 2025Article
- Dynamical variations, impact factors, and prediction of echinoco-ccosis in Xinjiang by ARIMA-Random Forest Hybrid Model.PloS one · 2025Article
- Human echinococcosis incidence in Canada: A retrospective descriptive study using administrative hospital and ambulatory visit data, 2000-2020.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024Article
- Current evidence of the economic value of One Health initiatives: A systematic literature review.One health (Amsterdam, Netherlands) · 2024Review
- Prevalence and geographic distribution of Echinococcus genus in wild canids in southern Québec, Canada.PloS one · 2024Article
- Seroprevalence of Cystic Echinococcosis in Yaks and Sheep During 2017 on the Qinghai-Tibet Plateau, China.Frontiers in veterinary science · 2022Article
- New geographic records forInternational journal for parasitology. Parasites and wildlife · 2021Article
- Treatment of a giant hepatic echinococcal cyst with percutaneous drainage and in vivo assessment of the protoscolicidal effect of praziquantel.Clinical journal of gastroenterology · 2021Article
- Echinococcal hepatic lesion mimicking metastasis from colon cancer: two case reports.BMC surgery · 2021Article
- Disseminated Echinococcus multilocularis Infection without Liver Involvement in Child, Canada, 2018.Emerging infectious diseases · 2020Article
- Disseminated alveolar echinococcosis in a 74-year-old woman presenting with focal seizure.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019Article
- A One Health systematic review of diagnostic tools forFood and waterborne parasitology · 2019Article
- Article
- Echinococcus in wild canids in Québec (Canada) and Maine (USA).PLoS neglected tropical diseases · 2018Article
- Seroprevalence of Human Cystic Echinococcosis in Alborz Province, Central Iran in 2015.Iranian journal of public health · 2018Article
- Control of Human Echinococcosis in Xinjiang, China, with 2,544 Surgeries in a Multihospital Network.The American journal of tropical medicine and hygiene · 2017Article
- Seroepidemiology of Human Hydatidosis Using AgB-ELISA Test in Isfahan City and Suburb Areas, Isfahan Province, Central Iran.Iranian journal of public health · 2015Article
- Epidemiological and Clinical Characteristics of Patients with Hydatid Cysts in Khorasan Razavi Province, from 2011 to 2014.Iranian journal of parasitologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Echinococcosis is a rare but endemic condition in people in Canada, caused by a zoonotic cestode for which the source of human infection is ingestion of parasite eggs shed by canids. The objectives of this study were to identify risk factors associated with infection and to measure the cost-utility of introducing an echinococcosis prevention program in a rural area. We analyzed human case reports submitted to the Canadian Institutes for Health Information between 2002 and 2011. Over this 10 year period, there were 48 cases associated with E. granulosus/E. canadensis, 16 with E. multilocularis, and 251 cases of echinococcosis for which species was not identified (total 315 cases). Nationally, annual incidence of echinococcosis was 0.14 cases per 100,000 people, which is likely an underestimate due to under-diagnosis and under-reporting. Risk factors for echinococcosis included female gender, age (>65 years), and residing in one of the northern territories (Nunavut, Yukon, or Northwest Territories). The average cost of treating a case of cystic echinococcosis in Canada was $8,842 CAD. Cost-utility analysis revealed that dosing dogs with praziquantel (a cestocide) at six week intervals to control cystic echinococcosis is not currently cost-effective at a threshold of $20,000-100,000 per Quality Adjusted Life Year (QALY) gained, even in a health region with the highest incidence rate in Canada ($666,978-755,051 per QALY gained). However, threshold analysis demonstrated that the program may become cost-saving at an echinococcosis incidence of 13-85 cases per 100,000 people and therefore, even one additional CE case in a community of 9000 people could result in the monetary benefits of the program outweighing costs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.