ArticleWorld journal of urology2016
The morbidity of laparoscopic radical cystectomy: analysis of postoperative complications in a multicenter cohort by the European Association of Urology (EAU)-Section of Uro-Technology.
Article in World journal of urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- The impact of preoperative nutritional status on post-surgical complication and mortality rates in patients undergoing radical cystectomy for bladder cancer: a systematic review of the literature.World journal of urology · 2021Pooled it
- Uretero-enteric strictures after cystectomy: revealing the modifiable risk factors.The Canadian journal of urology · 2026Article
- Extreme body mass index is associated with poor survival outcomes after radical cystectomy: a retrospective cohort study in a Chinese population.Translational andrology and urology · 2021Article
- Risk factors of postoperative ileus following laparoscopic radical cystectomy and developing a points-based risk assessment scale.Translational andrology and urology · 2021Article
- Bladder Cancer at the time of COVID-19 Outbreak.International braz j urol : official journal of the Brazilian Society of Urology · 2020Review
- Laparoscopic versus open radical cystectomy in the treatment of locally advanced T3 and T4 bladder cancer: Perioperative and Mid-term oncological outcomes.Turkish journal of urology · 2020Article
- Laparoscopic radical cystectomy in octogenarians: analysis of a Japanese multicenter cohort.International journal of clinical oncology · 2019Article
- Does previous abdominal surgery adversely affect perioperative and oncologic outcomes of laparoscopic radical cystectomy?World journal of surgical oncology · 2018Article
- Peri-operative allogeneic blood transfusion and outcomes after radical cystectomy: a population-based study.World journal of urology · 2017Article
- Mild to moderate intra-abdominal hypertension: Does it matter?World journal of critical care medicine · 2016Review
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Authors and funding
16 authors at 11 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze postoperative complications after laparoscopic radical cystectomy (LRC) and evaluate its risk factors in a large prospective cohort built by the ESUT across European centers involved in minimally invasive urology in the last decade.
methodsPatients were prospectively enrolled, and data were retrospectively analyzed. Only oncologic cases were included. There were no formal contraindications for LRC: Also patients with locally advanced tumors (pT4a), serious comorbidities, and previous major abdominal surgery were enrolled. All procedures were performed via a standard laparoscopic approach, with no robotic assistance. Early and late postoperative complications were graded according to the modified Clavien-Dindo classification. Multivariate logistic regression was performed to explore possible risk factors for developing complications.
resultsA total of 548 patients were available for final analysis, of which 258 (47%) experienced early complications during the first 90 days after LRC. Infectious, gastrointestinal, and genitourinary were, respectively, the most frequent systems involved. Postoperative ileus occurred in 51/548 (9.3%) patients. A total of 65/548 (12%) patients underwent surgical re-operation, and 10/548 (2%) patients died in the early postoperative period. Increased BMI (p = 0.024), blood loss (p = 0.021), and neoadjuvant treatment (p = 0.016) were significantly associated with a greater overall risk of experiencing complications on multivariate logistic regression. Long-term complications were documented in 64/548 (12%), and involved mainly stenosis of the uretero-ileal anastomosis or incisional hernias.
conclusionsIn this multicenter, prospective, large database, LRC appears to be a safe but morbid procedure. Standardized complication reporting should be encouraged to evaluate objectively a surgical procedure and permit comparison across studies.
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