Evidence map›Paper›PMID 26135005›Full record

ReviewCellular microbiology2015

The innate immune response in human tuberculosis.

Thomas R Lerner, Sophie Borel, Maximiliano G Gutierrez

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 3 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Delayed-Type Hypersensitivity toInternational journal of molecular sciences · 2026
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Protein-Mediated Virulence in Mycobacterium tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. MedComm · 2023
    Review
  20. Review

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas R LernerMill Hill Laboratory, The Francis Crick Institute, London, UK.
Sophie BorelMill Hill Laboratory, The Francis Crick Institute, London, UK.
Maximiliano G GutierrezMill Hill Laboratory, The Francis Crick Institute, London, UK.
The Francis Crick Institute · GB

Funding

Medical Research Council MC_UP_1202/11Wellcome Trust
6 · The paper itself

Abstract

Mycobacterium tuberculosis (Mtb) infection can be cleared by the innate immune system before the initiation of an adaptive immune response. This innate protection requires a variety of robust cell autonomous responses from many different host immune cell types. However, Mtb has evolved strategies to circumvent some of these defences. In this mini-review, we discuss these host-pathogen interactions with a focus on studies performed in human cells and/or supported by human genetics studies (such as genome-wide association studies).

Indexed as

Host-Pathogen InteractionsImmunity, InnateGenome-Wide Association StudyHumansImmune EvasionMycobacterium tuberculosisTuberculosis

Identifiers

PMID26135005
PMCPMC4832344
OpenAlexW1935953203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.