ReviewCold Spring Harbor perspectives in medicine2015
Initiation, Propagation, and Termination of Partial (Focal) Seizures.
Review in Cold Spring Harbor perspectives in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Data driven multiscale modelling of paroxysmal brain transitions using DC-coupled electrophysiological data.PloS one · 2026Article
- Using stereo-electroencephalography data to model the optimal intracranial venous sinus location for an endovascular seizure detection device: A feasibility study.Epilepsia open · 2025Article
- Spatiotemporal Brain Dynamics During Cyclic Seizures of Super-Refractory Status Epilepticus.European journal of neurology · 2025Article
- Rodent and human seizures demonstrate a dynamic interplay with spreading depolarizations.Neurobiology of disease · 2025Article
- Review
- The Power of ECG in Semi-Automated Seizure Detection in Addition to Two-Channel behind-the-Ear EEG.Bioengineering (Basel, Switzerland) · 2023Article
- Brivaracetam to Treat Partial Onset Seizures in Adults.Health psychology research · 2022Article
- Impact of DC-Coupled Electrophysiological Recordings for Translational Neuroscience: Case Study of Tracking Neural Dynamics in Rodent Models of Seizures.Frontiers in computational neuroscience · 2022Article
- Low EEG Gamma Entropy and Glucose Hypometabolism After Corpus Callosotomy Predicts Seizure Outcome After Subsequent Surgery.Frontiers in neurology · 2022Article
- Cenobamate, a Sodium Channel Inhibitor and Positive Allosteric Modulator of GABANeurology international · 2021Review
- Defining the latent period of epileptogenesis and epileptogenic zone in a focal cortical dysplasia type II (FCDII) rat model.Epilepsia · 2021Article
- Frequency-Dependent Dynamics of Functional Connectivity Networks During Seizure Termination in Childhood Absence Epilepsy: A Magnetoencephalography Study.Frontiers in neurology · 2021Article
- Hippocampal adult-born granule cells drive network activity in a mouse model of chronic temporal lobe epilepsy.Nature communications · 2020Article
- Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures.Brain : a journal of neurology · 2020Review
- Interictal epileptiform discharges shape large-scale intercortical communication.Brain : a journal of neurology · 2019Article
- GABAergic Interneurons in Seizures: Investigating Causality With Optogenetics.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2019Review
- Loss of neuronal network resilience precedes seizures and determines the ictogenic nature of interictal synaptic perturbations.Nature neuroscience · 2018Article
- A companion to the preclinical common data elements and case report forms for rodent EEG studies. A report of the TASK3 EEG Working Group of the ILAE/AES Joint Translational Task Force.Epilepsia open · 2018Article
- Low-voltage fast seizures in humans begin with increased interneuron firing.Annals of neurology · 2018Article
- Predictability and Resetting in a Case of Convulsive Status Epilepticus.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The neurophysiological patterns that correlate with partial (focal) seizures are well defined in humans by standard electroencephalogram (EEG) and presurgical depth electrode recordings. Seizure patterns with similar features are reproduced in animal models of partial seizures and epilepsy. However, the network determinants that support interictal spikes, as well as the initiation, progression, and termination of seizures, are still elusive. Recent findings show that inhibitory networks are prominently involved at the onset of these seizures, and that extracellular changes in potassium contribute to initiate and sustain seizure progression. The end of a partial seizure correlates with an increase in network synchronization, which possibly involves both excitatory and inhibitory mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.