Evidence map›Paper›PMID 26134738›Full record

ReviewAnnual review of chemical and biomolecular engineering2015

Microfluidic Strategies for Understanding the Mechanics of Cells and Cell-Mimetic Systems.

Joanna B Dahl, Jung-Ming G Lin, Susan J Muller, Sanjay Kumar

Abstract readReview
In one paragraph

Review in Annual review of chemical and biomolecular engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Scanning Ion Conductance Microscopy.Chemical reviews · 2021
    Review
  6. Article
  7. Article
  8. Microfabricated Devices for Confocal Microscopy on Biological Samples.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna B DahlDepartment of Chemical and Biomolecular Engineering.
Jung-Ming G Lin
Susan J Muller
Sanjay Kumar

Funding

Stem Cell Engineering Training ProgramT32GM098218 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD, SCHAFFER, DAVID V · 2011 to 2020
$1.8M
Molecular analysis of physical microenvironmental control of tumor cell invasionR21CA174573 · NCI · UNIVERSITY OF CALIFORNIA BERKELEY · PI KUMAR, SANJAY · 2014 to 2016
$655k
NCI NIH HHS R21 CA174573NCI NIH HHS R21CA174573NIGMS NIH HHS T32 GM098218NIGMS NIH HHS T32GM098218
6 · The paper itself

Abstract

Microfluidic systems are attracting increasing interest for the high-throughput measurement of cellular biophysical properties and for the creation of engineered cellular microenvironments. Here we review recent applications of microfluidic technologies to the mechanics of living cells and synthetic cell-mimetic systems. We begin by discussing the use of microfluidic devices to dissect the mechanics of cellular mimics, such as capsules and vesicles. We then explore applications to circulating cells, including erythrocytes and other normal blood cells, and rare populations with potential disease diagnostic value, such as circulating tumor cells. We conclude by discussing how microfluidic devices have been used to investigate the mechanics, chemotaxis, and invasive migration of adherent cells. In these ways, microfluidic technologies represent an increasingly important toolbox for investigating cellular mechanics and motility at high throughput and in a format that lends itself to clinical translation.

Indexed as

AnimalsArtificial CellsBiomechanical PhenomenaCell MovementCytological TechniquesEquipment DesignHumansMicrofluidic Analytical Techniquescapsuleschemotaxisdropletsmigrationparticlesvesicles

Identifiers

PMID26134738
PMCPMC5217707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.