Evidence map›Paper›PMID 26134624›Full record

ArticleJournal of human hypertension2016

Uric acid blood levels and relationship with the components of metabolic syndrome in hypertensive patients.

M V Papavasileiou, A G Karamanou, P Kalogeropoulos, G Moustakas, S Patsianis, A Pittaras

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Article in Journal of human hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M V PapavasileiouDepartment of Cardiology, Sismanoglio General Hospital, Athens, Greece.
A G KaramanouDepartment of Cardiology, Sismanoglio General Hospital, Athens, Greece.
P KalogeropoulosDepartment of Cardiology, Agioi Anargyroi General Hospital, Athens, Greece.
G MoustakasDepartment of Cardiology, Sismanoglio General Hospital, Athens, Greece.
S PatsianisDepartment of Cardiology, Sismanoglio General Hospital, Athens, Greece.
A PittarasDepartment of Cardiology, Mediton Cardiology Center, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Associations between high serum uric acid (SUA) levels and high blood pressure (BP), as well as between SUA levels and metabolic syndrome (MetS) have already been reported. The aim of the study was to investigate the relationship between the components of MetS with the SUA levels as also between SUA and apolipoproteins A1 and B (apoA1 and apoB) ratio in hypertensive patients. A total of 2577 consecutive hypertensive patients (1193 male and 1384 female) aged 57.5±13.3 years, were enrolled in our research. Samples were taken to measure SUA, glucose, triglycerides, high density lipoprotein (HDL-C), components of the MetS and apoA1 and apoB. The study population was divided into two groups: group A: SUA levels above normal range (men ⩾7 mg dl(-1), women ⩾6 mg dl(-1)) and group B: SUA levels within normal range. In the overall study population, SUA levels showed a statistically significant correlation with waist circumference (WC; r=0.293, P<0.000), triglycerides (r=0.197, P<0.000), glucose (r=0.085, P<0.000), apoB/apoA1 (r=0.136, P<0.000) and HDL-C (r=-0.235, P<0,001). In newly diagnosed untreated hypertensive patients there was also a statistically significant correlation of SUA levels with WC (r=0.331, P<0.001), triglycerides (r=0.228, P<0.001) apoB/apoA1 ratio (r=0.202, P<0.001) and HDL-C (r=-0.278, P<0.001). In hyperurecemic hypertensives there was a statistically significant correlation between SUA levels with WC (r=0.168, P=0.007), apoB/apoA1 ratio (r=0.256, P=0.003) and HDL-C (r=-0.202, P<0.001). SUA levels correlate significantly with all the components of MetS, as well as with the risk factor apoB/apoA1 ratio, in hypertensive patients.

Indexed as

Blood PressureAdultAgedApolipoprotein A-IApolipoprotein B-100BiomarkersBlood GlucoseCholesterol, HDLFemaleHumansHypertensionHyperuricemiaLipidsMaleMetabolic SyndromeMiddle AgedAPOA1 protein, humanAPOB protein, humanApolipoprotein A-IApolipoprotein B-100BiomarkersBlood GlucoseCholesterol, HDLLipidsTriglyceridesUric Acid

Identifiers

PMID26134624

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.