ArticleEndoscopy international open2014
Adverse events in older patients undergoing ERCP: a systematic review and meta-analysis.
Article in Endoscopy international open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography in Nonagenarians: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2022Pooled it
- Predictors of hemodynamic instability during ERCP sedation in older adults: impact of sedation strategy in a retrospective cohort.BMC geriatrics · 2026Article
- Association of ERCP Timing with Clinical Outcomes in Acute Cholangitis Secondary to Choledocholithiasis: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Comparison of the Clinical Course, Management and Outcomes of Acute Pancreatitis in Aged and Young Patients.Biomedicines · 2026Review
- Article
- Endoscopic retrograde cholangiopancreatography of geriatric patients with cholangitis: A single-center experience in central Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025Article
- Endoscopic retrograde cholangiopancreatography in elderly patients: Is age just a number or something more?World journal of gastroenterology · 2025Article
- Long-Term Patency of Plastic Stents in Elderly Patients with Common Bile Duct Stones: A Prospective Pilot Study.Journal of clinical medicine · 2025Article
- Optimal timing for discontinuation of ERCP in cases of difficult selective biliary cannulation.Endoscopy international open · 2025Article
- Clinical Features and Prognosis of Acute Cholangitis in Octogenarians: A Prospective Comparative Study.Medicina (Kaunas, Lithuania) · 2024Article
- Comparing percutaneous transhepatic papillary balloon dilation with endoscopic retrograde cholangiopancreatography in elderly patients for common bile duct stones: a 3-year retrospective study.Abdominal radiology (New York) · 2024Article
- Large common bile duct stones in high-risk elderly patients: Immediate endoscopic stone removal or elective stone removal? A single-center retrospective study.BMC gastroenterology · 2023Article
- ERCP in patients over 90 years old: Safety and efficacy comparison with a younger cohort.Endoscopy international open · 2023Article
- Safety and efficacy of remifentanil-propofol combination on "muscle relaxant-free" general anesthesia for therapeutic endoscopic retrograde cholangiopancreatography: a randomized controlled trial.American journal of translational research · 2023Article
- Safety of Nonagenarians Receiving Therapeutic ERCP, Single Center Experience.Journal of clinical medicine · 2022Article
- Endo-anesthesia: a primer.Gastroenterology report · 2022Review
- DOES AGE INFLUENCE IN ENDOSCOPIC THERAPEUTIC SUCCESS ON THE BILIARY TRACT?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022Article
- Risk factors for complications in elderly patients aged 85 years and over undergoing endoscopic biliary stone removal.Frontiers in surgery · 2022Article
- The efficacy and safety of colonoscopy in nonagenarians: A multicenter study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020Article
- Endoscopic retrograde cholangiopancreatography in elderly patients: Difficult cannulation and adverse events.World journal of clinical cases · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND STUDY
aimsBiliary and pancreatic diseases are common in the elderly; however, few studies have addressed the occurrence of adverse events in elderly patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Our objective was to determine the incidence rates of specific adverse events in this group and calculate incidence rate ratios (IRRs) for selected comparison groups. PATIENTS AND
methodsBibliographical searches were conducted in Medline, EMBASE, and Cochrane library databases. The studies included documented the incidence of adverse events (perforation, pancreatitis, bleeding, cholangitis, cardiopulmonary adverse events, mortality) in patients aged ≥ 65 who underwent ERCP. Pooled incidence rates were calculated for each reported adverse event and IRRs were determined for available comparison groups. A parallel analysis was performed in patients aged ≥ 80 and ≥ 90.
resultsOur literature search yielded 7429 articles, of which 69 studies met our inclusion criteria. Pooled incidence rates for adverse events (per 1000 ERCPs) in patients aged ≥ 65 were as follows: perforation 3.8 (95 %CI 1.8 - 7.0), pancreatitis 13.1 (95 %CI 11.0 - 15.5), bleeding 7.7 (95 %CI 5.7 - 10.1), cholangitis 16.1 (95 %CI 11.7 - 21.7), cardiopulmonary events 3.7 (95 %CI 1.5 - 7.6), and death 7.1 (95 %CI 5.2 - 9.4). Patients ≥ 65 had lower rates of pancreatitis (IRR 0.3, 95 %CI 0.3 - 0.4) compared with younger patients. Octogenarians had higher rates of death (IRR 2.4, 95 %CI 1.3 - 4.5) compared with younger patients, whereas nonagenarians had increased rates of bleeding (IRR 2.4, 95 %CI 1.1 - 5.2), cardiopulmonary events (IRR 3.7, 95 %CI 1.0 - 13.9), and death (IRR 3.8, 95 %CI 1.0 - 14.4). Conclusions ERCP appears to be safe in elderly patients, except in the very elderly who are at higher risk of some adverse events. These data on adverse event rates can help to inform clinical decision-making, the consent process, and comparative effectiveness analyses.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.