Evidence map›Paper›PMID 26134556›Full record

ArticleRespirology (Carlton, Vic.)2015

Lung function and exhaled nitric oxide in healthy unsedated African infants.

Diane Gray, Lauren Willemse, Ane Visagie, Emilee Smith, Dorottya Czövek, Peter D Sly, Zoltán Hantos, Graham L Hall, Heather J Zar

Abstract read
In one paragraph

Article in Respirology (Carlton, Vic.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Diane GrayDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
Lauren WillemseDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
Ane VisagieDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.
Emilee SmithDivision of Epidemiology and Biostatistics, School of Public Health and Family, University of Cape Town, Cape Town, South Africa.
Dorottya CzövekDepartment of Medical Physics and Informatics, University of Szeged, Szeged, Hungary.
Peter D SlyQueensland Children's Medical Research Institute, University of Queensland, Perth, Western Australia, Australia.
Zoltán HantosDepartment of Medical Physics and Informatics, University of Szeged, Szeged, Hungary.
Graham L HallTelethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia.
Heather J ZarDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

Funding

Wellcome TrustWellcome Trust 098479/z/12/2
6 · The paper itself

Abstract

BACKGROUND AND

objectivePopulation-appropriate lung function reference data are essential to accurately identify respiratory disease and measure response to interventions. There are currently no reference data in African infants. The aim was to describe normal lung function in healthy African infants.

methodsLung function was performed on healthy South African infants enrolled in a birth cohort study, the Drakenstein child health study. Infants were excluded if they were born preterm or had a history of neonatal respiratory distress or prior respiratory tract infection. Measurements, made during natural sleep, included the forced oscillation technique, tidal breathing, exhaled nitric oxide and multiple breath washout measures.

resultsThree hundred sixty-three infants were tested. Acceptable and repeatable measurements were obtained in 356 (98%) and 352 (97%) infants for tidal breathing analysis and exhaled nitric oxide outcomes, 345 (95%) infants for multiple breath washout and 293 of the 333 (88%) infants for the forced oscillation technique. Age, sex and weight-for-age z score were significantly associated with lung function measures.

conclusionsThis study provides reference data for unsedated infant lung function in African infants and highlights the importance of using population-specific data.

Indexed as

Nitric OxideRespiratory Function TestsCohort StudiesExhalationFemaleHumansInfantMaleReference ValuesSleepSouth AfricaNitric OxideAfricaninfantslung functionreference data

Identifiers

PMID26134556
PMCPMC4623783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.