ArticleScientific reports2015
Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 57 citations in OpenAlex.
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- Impact of UV-C Irradiation on Bacterial Disinfection in a Drinking Water Purification System.Journal of microbiology and biotechnology · 2023Article
- Water as a Probe for Standardization of Near-Infrared Spectra by Mutual-Individual Factor Analysis.Molecules (Basel, Switzerland) · 2022Article
- N-Doped graphene quantum dots (N-GQDs) as fluorescent probes for detection of UV induced DNA damage.RSC advances · 2022Article
- Immunotherapy for the Treatment of Squamous Cell Carcinoma: Potential Benefits and Challenges.International journal of molecular sciences · 2022Review
- Lignin Nanoparticles Deliver Novel Thymine Biomimetic Photo-Adducts with Antimelanoma Activity.International journal of molecular sciences · 2022Article
- Chemometrics: An Excavator in Temperature-Dependent Near-Infrared Spectroscopy.Molecules (Basel, Switzerland) · 2022Review
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- Worenine Prevents Solar Ultraviolet-Induced Sunburn by Inhibiting JNK2.Frontiers in pharmacology · 2022Article
- Effect of Cold Atmospheric Plasma on Epigenetic Changes, DNA Damage, and Possibilities for Its Use in Synergistic Cancer Therapy.International journal of molecular sciences · 2021Review
- A Novel Tool for Visualization of Water Molecular Structure and Its Changes, Expressed on the Scale of Temperature Influence.Molecules (Basel, Switzerland) · 2020Article
- Application of Laser-Induced Breakdown Spectroscopy in Detection of Cadmium Content in Rice Stems.Frontiers in plant science · 2020Article
- Aquaphotomics-From Innovative Knowledge to Integrative Platform in Science and Technology.Molecules (Basel, Switzerland) · 2019Review
- Essentials of Aquaphotomics and Its Chemometrics Approaches.Frontiers in chemistry · 2018Article
- Effects of photodynamic therapy on dermal fibroblasts from xeroderma pigmentosum and Gorlin-Goltz syndrome patients.Oncotarget · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ultraviolet (UV) radiation causes cellular DNA damage, among which cyclobutane pyrimidine dimers (CPDs) are responsible for a variety of genetic mutations. Although several approaches have been developed for detection of CPDs, conventional methods require time-consuming steps. Aquaphotomics, a new approach based on near-infrared spectroscopy (NIRS) and multivariate analysis that determines interactions between water and other components of the solution, has become an effective method for qualitative and quantitative parameters measurement in the solutions. NIR spectral patterns of UVC-irradiated and nonirradiated DNA solutions were evaluated using aquaphotomics for detection of UV-induced CPDs. Groups of UV-irradiated and nonirradiated DNA samples were classified (87.5% accuracy) by soft independent modeling of class analogy (SIMCA). A precise regression model calculated from NIR water spectral patterns based on UVC doses (r Val = 0.9457) and the concentration of cis-syn cyclobutane thymine dimers (cis-syn T<>Ts; r Val = 0.9993) was developed using partial least squares regression (PLSR), while taking advantage of water spectral patterns, particularly around 1400-1500 nm. Our results suggested that, in contrast to DNA, the formation of cis-syn T<>Ts increased the strongly hydrogen bonded water. Additionally, NIRS could qualitatively and quantitatively detect cis-syn T<>Ts in isolated DNA aqueous solutions upon UVC exposure.
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