Evidence map›Paper›PMID 26133021›Full record

ArticleEpidemiology (Cambridge, Mass.)2015

Brief Report: Incubation Period Duration and Severity of Clinical Disease Following Severe Acute Respiratory Syndrome Coronavirus Infection.

Victor Virlogeux, Vicky J Fang, Joseph T Wu, Lai-Ming Ho, J S Malik Peiris, Gabriel M Leung, Benjamin J Cowling

Abstract read
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Article
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  12. Incubation period for COVID-19: a systematic review and meta-analysis.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
    Review
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  15. Article
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  18. Severe case of covid-19 infection in children: Case report.Annals of medicine and surgery (2012) · 2021
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victor VirlogeuxFrom the aDepartment of Biology, Ecole Normale Supérieure de Lyon, Lyon, France; bWHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, and cCentre of Influenza Research, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Vicky J Fang
Joseph T Wu
Lai-Ming Ho
J S Malik Peiris
Gabriel M Leung
Benjamin J Cowling

Funding

Understanding and controlling antibiotic resistanceU54GM088558 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HANAGE, WILLIAM · 2009 to 2018
$26.4M
NIGMS NIH HHS U54 GM088558
6 · The paper itself

Abstract

backgroundFew previous studies have investigated the association between the severity of an infectious disease and the length of incubation period.

methodsWe estimated the association between the length of the incubation period and the severity of infection with the severe acute respiratory syndrome coronavirus, using data from the epidemic in 2003 in Hong Kong.

resultsWe estimated the incubation period of severe acute respiratory syndrome based on a subset of patients with available data on exposure periods and a separate subset of patients in a putative common source outbreak, and we found associations between shorter incubation period and greater severity in both groups after adjusting for potential confounders.

conclusionsOur findings suggest that patients with a shorter incubation period went on to have more severe disease. Further studies are needed to investigate potential biological mechanisms for this association.

Indexed as

Infectious Disease Incubation PeriodSeverity of Illness IndexAdolescentAdultAgedAged, 80 and overBayes TheoremDatabases, FactualEpidemicsFemaleHong KongHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle Aged

Identifiers

PMID26133021
PMCPMC4889459

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.