ArticleMolecular ecology2015
Seeking signatures of reinforcement at the genetic level: a hitchhiking mapping and candidate gene approach in the house mouse.
Article in Molecular ecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- Testing the genomic overlap between intraspecific mating traits and interspecific mating barriers.Evolution letters · 2024Article
- Genomes of Microtus Rodents Highlight the Importance of Olfactory and Immune Systems in Their Fast Radiation.Genome biology and evolution · 2024Article
- Do genetic loci that cause reproductive isolation in the lab inhibit gene flow in nature?Evolution; international journal of organic evolution · 2024Article
- Genomic analysis of the rhesus macaque (Ecology and evolution · 2023Article
- The population genetics of speciation by cascade reinforcement.Ecology and evolution · 2023Article
- Regulation of Sexually Dimorphic Expression of Major Urinary Proteins.Frontiers in physiology · 2022Review
- Neurogenomic divergence during speciation by reinforcement of mating behaviors in chorus frogs (Pseudacris).BMC genomics · 2021Article
- The role of copy-number variation in the reinforcement of sexual isolation between the two European subspecies of the house mouse.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals.Genome biology and evolution · 2020Article
- Genomic Signatures of Reinforcement.Genes · 2018Review
- Molecular heterogeneity in major urinary proteins of Mus musculus subspecies: potential candidates involved in speciation.Scientific reports · 2017Article
- Genetic signatures of natural selection in a model invasive ascidian.Scientific reports · 2017Article
- Hybridization in Plants: Old Ideas, New Techniques.Plant physiology · 2017Review
- Diversity of major urinary proteins (MUPs) in wild house mice.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Reinforcement is the process by which prezygotic isolation is strengthened as a response to selection against hybridization. Most empirical support for reinforcement comes from the observation of its possible phenotypic signature: an accentuated degree of prezygotic isolation in the hybrid zone as compared to allopatry. Here, we implemented a novel approach to this question by seeking for the signature of reinforcement at the genetic level. In the house mouse, selection against hybrids and enhanced olfactory-based assortative mate preferences are observed in a hybrid zone between the two European subspecies Mus musculus musculus and M. m. domesticus, suggesting a possible recent reinforcement event. To test for the genetic signature of reinforcing selection and identify genes involved in sexual isolation, we adopted a hitchhiking mapping approach targeting genomic regions containing candidate genes for assortative mating in mice. We densely scanned these genomic regions in hybrid zone and allopatric samples using a large number of fast evolving microsatellite loci that allow the detection of recent selection events. We found a handful of loci showing the expected pattern of significant reduction in variability in populations close to the hybrid zone, showing assortative odour preference in mate choice experiments as compared to populations further away and displaying no such preference. These loci lie close to genes that we pinpoint as testable candidates for further investigation.
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