Evidence map›Paper›PMID 26132277›Full record

ReviewAnnals of the New York Academy of Sciences2015

Impact of diabetes on cognitive function and brain structure.

Amir Moheet, Silvia Mangia, Elizabeth R Seaquist

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of the New York Academy of Sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 252 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
252citing papers in PubMed, 13 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

252 citing papers in PubMed, 13 syntheses or guidelines pooled it, 500 citations in OpenAlex.

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192 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Amir MoheetDivision of Endocrinology and Diabetes, Department of Medicine.
Silvia MangiaCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
Elizabeth R SeaquistDivision of Endocrinology and Diabetes, Department of Medicine.
Diabetes Australia · AUResonance Research (United States) · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)KL2TR000113 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$5.4M
Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 DiabetesR01DK099137 · NIDDK · UNIVERSITY OF MINNESOTA · PI MANGIA, SILVIA · 2014 to 2018
$2.5M
NCATS NIH HHS 5KL2TR000113NCATS NIH HHS KL2 TR000113NIDDK NIH HHS R01 DK099137
6 · The paper itself

Abstract

Both type 1 and type 2 diabetes have been associated with reduced performance on multiple domains of cognitive function and with structural abnormalities in the brain. With an aging population and a growing epidemic of diabetes, central nervous system-related complications of diabetes are expected to rise and could have challenging future public health implications. In this review, we will discuss the brain structural and functional changes that have been associated with type 1 and type 2 diabetes. Diabetes duration and glycemic control may play important roles in the development of cognitive impairment in diabetes, but the exact underlying pathophysiological mechanisms causing these changes in cognition and structure are not well understood. Future research is needed to better understand the natural history and the underlying mechanisms, as well as to identify risk factors that predict who is at greatest risk of developing cognitive impairment. This information will lead to the development of new strategies to minimize the impact of diabetes on cognitive function.

Indexed as

CognitionBrainDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Humansbraincognitive dysfunctionmemorytype 1 diabetes mellitustype 2 diabetes mellitus

Identifiers

PMID26132277
PMCPMC4837888
OpenAlexW2123416594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.