ArticlePloS one2015
Time of HIV Diagnosis and Engagement in Prenatal Care Impact Virologic Outcomes of Pregnant Women with HIV.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 53 citations in OpenAlex.
- Article
- Article
- Article
- Factors associated with loss to follow up among HIV-exposed children: a historical cohort study from 2000 to 2017, in Porto Alegre, Brazil.BMC public health · 2022Article
- Prevalence of the Human Immunodeficiency Virus and associated factors in pregnant women in the state of Pará.Revista brasileira de enfermagem · 2022Article
- Longitudinal Bidirectional Relations among Parenting Quality, Parenting Stress, and Child Functioning in HIV-affected Families.Journal of youth and adolescence · 2021Article
- Association Between Household and Maternal Socioeconomic Factors with Birth Outcomes in the Democratic Republic of Congo and South Africa: A Comparative Study.Maternal and child health journal · 2021Article
- A Mixed-Methods Longitudinal Investigation of Mothers' Disclosure of HIV to Their Children.Child development · 2021Article
- Unintended pregnancy and viral suppression in pregnant women living with HIV.American journal of obstetrics & gynecology MFM · 2021Article
- Association of Adverse Neighborhood Exposures With HIV Viral Load in Pregnant Women at Delivery.JAMA network open · 2020Article
- Harnessing early life immunity to develop a pediatric HIV vaccine that can protect through adolescence.PLoS pathogens · 2020Article
- Mother-to-Child HIV Transmission With In Utero Dolutegravir vs. Efavirenz in Botswana.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Pediatric HIV: the Potential of Immune Therapeutics to Achieve Viral Remission and Functional Cure.Current HIV/AIDS reports · 2020Review
- Time of HIV diagnosis, CD4 count and viral load at antenatal care start and delivery in South Africa.PloS one · 2020Article
- Reasons for late presentation for antenatal care, healthcare providers' perspective.BMC health services research · 2019Article
- HIV care continuum outcomes of pregnant women living with HIV with and without depression.AIDS care · 2018Article
- Evaluating outcomes of mother-infant pairs using dolutegravir for HIV treatment during pregnancy.AIDS (London, England) · 2018Article
- Article
- Pregnant with HIV before age 25: data from a large national study in Italy, 2001-2016.Epidemiology and infection · 2017Article
- Evolving treatment implementation among HIV-infected pregnant women and their partners: results from a national surveillance study in Italy, 2001-2015.Journal of global health · 2017Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHIV suppression at parturition is beneficial for maternal, fetal and public health. To eliminate mother-to-child transmission of HIV, an understanding of missed opportunities for antiretroviral therapy (ART) use during pregnancy and HIV suppression at delivery is required. METHODOLOGY: We performed a retrospective analysis of 836 mother-to-child pairs involving 656 HIV-infected women in Philadelphia, 2005-2013. Multivariable regression examined associations between patient (age, race/ethnicity, insurance status, drug use) and clinical factors such as adequacy of prenatal care measured by the Kessner index which classifies prenatal care as inadequate, intermediate, or adequate prenatal care; timing of HIV diagnosis; and the outcomes: receipt of ART during pregnancy and viral suppression at delivery.
resultsOverall, 25% of the sample was diagnosed with HIV during pregnancy; 39%, 38%, and 23% were adequately, intermediately, and inadequately engaged in prenatal care. Eight-five percent of mother-to-child pairs received ART during pregnancy but only 52% achieved suppression at delivery. Adjusting for patient factors, pairs diagnosed with HIV during pregnancy were less likely to receive ART (AOR 0.39, 95% CI 0.25-0.61) and achieve viral suppression (AOR 0.70, 95% CI 0.49-1.00) than those diagnosed before pregnancy. Similarly, women with inadequate prenatal care were less likely to receive ART (AOR 0.06, 95% CI 0.03-0.11) and achieve viral suppression (AOR 0.31, 95% CI 0.20-0.47) than those with adequate prenatal care.
conclusionsTargeted interventions to diagnose HIV prior to pregnancy and engage HIV-infected women in prenatal care have the potential to improve HIV related outcomes in the perinatal period.
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