Evidence map›Paper›PMID 26131613›Full record

ReviewPathogens (Basel, Switzerland)2015

Molecular Characterization of the Multidrug Resistant Escherichia coli ST131 Clone.

Mark A Schembri, Nouri L Ben Zakour, Minh-Duy Phan, Brian M Forde, Mitchell Stanton-Cook, Scott A Beatson

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Whole-genome analysis of fiveMicrobiology spectrum · 2025
    Article
  5. Article
  6. An ovine septic shock model of live bacterial infusion.Intensive care medicine experimental · 2024
    Article
  7. Review
  8. Decolonizing drug-resistantMicrobiology (Reading, England) · 2023
    Article
  9. Article
  10. Pathogenicity Islands in UropathogenicAntibiotics (Basel, Switzerland) · 2022
    Article
  11. Comparative genomic analysis of ESBL-producingJAC-antimicrobial resistance · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Antimicrobial Resistance in ESKAPE Pathogens.Clinical microbiology reviews · 2020
    Review
  17. Characterization ofAntimicrobial agents and chemotherapy · 2020
    Article
  18. Prevalence ofInternational journal of microbiology · 2020
    Article
  19. Article
  20. Repeated Isolation of Extended-Spectrum-β-Lactamase-PositiveAntimicrobial agents and chemotherapy · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mark A SchembriSchool of Chemistry & Molecular Biosciences, the University of Queensland, Brisbane, Queensland 4072, Australia. m.schembri@uq.edu.au.
Nouri L Ben ZakourSchool of Chemistry & Molecular Biosciences, the University of Queensland, Brisbane, Queensland 4072, Australia. n.benzakour@uq.edu.au.
Minh-Duy PhanSchool of Chemistry & Molecular Biosciences, the University of Queensland, Brisbane, Queensland 4072, Australia. m.phan1@uq.edu.au.
Brian M FordeSchool of Chemistry & Molecular Biosciences, the University of Queensland, Brisbane, Queensland 4072, Australia. b.forde@uq.edu.au.
Mitchell Stanton-CookSchool of Chemistry & Molecular Biosciences, the University of Queensland, Brisbane, Queensland 4072, Australia. m.stantoncook@uq.edu.au.
Scott A BeatsonSchool of Chemistry & Molecular Biosciences, the University of Queensland, Brisbane, Queensland 4072, Australia. s.beatson@uq.edu.au.
University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Escherichia coli ST131 is a recently emerged and globally disseminated multidrug resistant clone associated with urinary tract and bloodstream infections in both community and clinical settings. The most common group of ST131 strains are defined by resistance to fluoroquinolones and possession of the type 1 fimbriae fimH30 allele. Here we provide an update on our recent work describing the globally epidemiology of ST131. We review the phylogeny of ST131 based on whole genome sequence data and highlight the important role of recombination in the evolution of this clonal lineage. We also summarize our findings on the virulence of the ST131 reference strain EC958, and highlight the use of transposon directed insertion-site sequencing to define genes associated with serum resistance and essential features of its large antibiotic resistance plasmid pEC958.

Indexed as

antibiotic resistanceFimHgenomicsplasmidST131TraDISurinary tracturopathogenic Escherichia colivirulence

Identifiers

PMID26131613
PMCPMC4584265
OpenAlexW1556796966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.