ArticleIranian journal of pediatric hematology and oncology2015
Prevalence and specificities of red cell alloantibodies in transfusion-dependent beta thalassemia patients in Yazd.
Article in Iranian journal of pediatric hematology and oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Red blood cell alloimmunisation in transfusion-dependent thalassaemia: a systematic review.Blood transfusion = Trasfusione del sangue · 2019Pooled it
- Red blood cell alloimmunization in transfusion-dependent β-thalassemia major patients in Eastern Iran.Annals of hematology · 2026Article
- Microfluidic chip designs and their application for E antigen typing on red blood cells.RSC advances · 2025Article
- Study of the Frequency and Specificity of Red Cell Antibodies in Patients with Hemoglobinopathies.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023Article
- Red Blood Cell Immunization and Contributing Factors in 685 Thalassemia Patients.International journal of hematology-oncology and stem cell research · 2022Article
- Prevalence and specificity of red blood cell alloantibodies and autoantibodies in transfused Iranian β-thalassemia patients: A systematic review and meta-analysis.Asian journal of transfusion scienceReview
- Red blood cell alloimmunization in Iran: A Comprehensive review of the literature.Asian journal of transfusion scienceReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. In this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. MATERIALS AND
methodsIn this cross-sectional study, overall of 100 thalassemia patients from Yazd thalassemia clinic were recruited from July to September 2013. Two blood samples with volume of 6 ml were collected from each patient for standard tube and gel method antibody screening tests and a questionnaire consisting of demographic, health and blood transfusion status was completed.
resultsOut of 100 cases, 54 were female (54%) and 46 male (46%). The patients' age mean was 14.97±7.91 years with 2 to 33 years age range. Only 4% (n=4) had developed alloantibodies. (One patient developed dual alloantibody (Anti-C and Anti-D) and three patients developed single alloantibody (Anti-K)).Gel method detected 4 patients with alloantibody but in two patients not detected by the standard tube method.
conclusionThe prevalence of RBC alloantibody production in this study was less than most previous studies. Anti-K was the most prevalent alloantibody in thalassemia patients in Yazd. It seems Rh and Kell blood group phenotyping in a newly diagnosed thalassemia patient and selection of matched blood for transfusion is very important.
Indexed as
Identifiers
26131348PMC4475630W406645369What OpenQuestion holds
Registered trials
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