Evidence map›Paper›PMID 26131326›Full record

ReviewWorld journal of diabetes2015

Diabetes mellitus: The epidemic of the century.

Akram T Kharroubi, Hisham M Darwish

4 registry-linked trialsAbstract readReview
In one paragraph

Review in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 379 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
379citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04444570 unknown statusnot on this mapstarted 2021, after this paper: background citation

Continuous Glycemia Monitoring in Perioperative Period in Patients Undergoing Total Knee or Hip Arthroplasty: a Protocol of Observational Study

TypeobservationalSponsorMedical University of WarsawRan2021 to 2022Enrolled100ConditionsOsteoarthritis, Knee, Osteoarthritis, Hip, Hyperglycemia, Diabetes Mellitus, Type 2ArmsContinuous glycemia measuring device (Dexcom) implantation into the subcutaneous tissue
NCT05079529 phase2unknown statusnot on this mapstarted 2021, after this paper: background citation

Development The Potentiality of β-1,3/1,6-D-Glucan (Polysaccharide Peptide) From Mycelia Extract of Indonesia's Ganoderma Lucidum as Adjuvant Therapy in Patients With Cardiometabolic Syndrome Based on NCEP-ATP III Criteria With Modification on Obesity Classification (Waist Circumference Measurement) for Asian Population

TypeinterventionalSponsorUniversity of BrawijayaRan2021 to 2022Enrolled70ConditionsCardiometabolic SyndromeArmsβ-1,3/1,6-D-Glucan From Mycelia Extract of Indonesia's Ganoderma Lucidum Group, Placebo Group
NCT05291026 nacompletednot on this mapstarted 2018, after this paper: background citation

Evaluation of mHealth Intervention to Improve Medication Adherence in Type 2 Diabetes in Nigeria: a Randomized Controlled Trial

TypeinterventionalSponsorObafemi Awolowo UniversityRan2018 to 2019Enrolled120ConditionsDiabetes MellitusArmsmobile phone-based health information
NCT05550870 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Raw Versus Roasted Fenugreek Seed Powder in Reducing Blood Glucose Levels in Type 2 Diabetic Patients

TypeinterventionalSponsorUniversity of Veterinary and Animal Sciences, Lahore - PakistanRan2022 to 2022Enrolled35ConditionsType 2 DiabetesArmsRaw fenugreek seed powder, Roasted fenugreek seed powder
3 · Its place in the literature

Who cites it

379 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Review
  20. Metabolite profiling and molecular dynamics-basedFrontiers in plant science · 2026
    Article

319 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Akram T KharroubiAkram T Kharroubi, Department of Medical Laboratory Sciences, Faculty of Health Professions, Al-Quds University, Jerusalem 91000, Palestine.
Hisham M DarwishAkram T Kharroubi, Department of Medical Laboratory Sciences, Faculty of Health Professions, Al-Quds University, Jerusalem 91000, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas, the Western Pacific region has the highest number of adults diagnosed with diabetes and has countries with the highest prevalence of diabetes (37.5%). Different classes of diabetes mellitus, type 1, type 2, gestational diabetes and other types of diabetes mellitus are compared in terms of diagnostic criteria, etiology and genetics. The molecular genetics of diabetes received extensive attention in recent years by many prominent investigators and research groups in the biomedical field. A large array of mutations and single nucleotide polymorphisms in genes that play a role in the various steps and pathways involved in glucose metabolism and the development, control and function of pancreatic cells at various levels are reviewed. The major advances in the molecular understanding of diabetes in relation to the different types of diabetes in comparison to the previous understanding in this field are briefly reviewed here. Despite the accumulation of extensive data at the molecular and cellular levels, the mechanism of diabetes development and complications are still not fully understood. Definitely, more extensive research is needed in this field that will eventually reflect on the ultimate objective to improve diagnoses, therapy and minimize the chance of chronic complications development.

Indexed as

Classification of diabetesDiabetesDiagnosisEtiologyGeneticsGestational diabetesType 1 diabetesType 2 diabetes

Identifiers

PMID26131326
PMCPMC4478580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.