Evidence map›Paper›PMID 26131309›Full record

ArticleWorld journal of stem cells2015

Mesenchymal stem cells: A new diagnostic tool?

Maria Teresa Valenti, Antonio Mori, Giovanni Malerba, Luca Dalle Carbonare

Open access · hybridAbstract read
In one paragraph

Article in World journal of stem cells, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Ectopic expression of the osteogenic master geneWorld journal of stem cells · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Maria Teresa ValentiMaria Teresa Valenti, Antonio Mori, Luca Dalle Carbonare, Department of Medicine, Section of Internal Medicine D, University of Verona, 37134 Verona, Italy.
Antonio MoriMaria Teresa Valenti, Antonio Mori, Luca Dalle Carbonare, Department of Medicine, Section of Internal Medicine D, University of Verona, 37134 Verona, Italy.
Giovanni MalerbaMaria Teresa Valenti, Antonio Mori, Luca Dalle Carbonare, Department of Medicine, Section of Internal Medicine D, University of Verona, 37134 Verona, Italy.
Luca Dalle CarbonareMaria Teresa Valenti, Antonio Mori, Luca Dalle Carbonare, Department of Medicine, Section of Internal Medicine D, University of Verona, 37134 Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are progenitor cells capable of self-renewal that can differentiate in multiple tissues and, under specific and standardized culture conditions, expand in vitro with little phenotypic alterations. In recent years, preclinical and clinical studies have focused on MSC analysis and understanding the potential use of these cells as a therapy in a wide range of pathologies, and many applications have been tested. Clinical trials using MSCs have been performed (e.g., for cardiac events, stroke, multiple sclerosis, blood diseases, auto-immune disorders, ischemia, and articular cartilage and bone pathologies), and for many genetic diseases, these cells are considered an important resource. Considering of the biology of MSCs, these cells may also be useful tools for understanding the physiopathology of different diseases, and they can be used to develop specific biomarkers for a broad range of diseases. In this editorial, we discuss the literature related to the use of MSCs for diagnostic applications and we suggest new technologies to improve their employment.

Indexed as

BiomarkersDiagnostic toolMesenchymal stem cellsNext generation sequencingTumor-initiating cells

Identifiers

PMID26131309
PMCPMC4478625
OpenAlexW2399232399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.