Evidence map›Paper›PMID 26131295›Full record

ArticleInternational journal of clinical and experimental medicine2015

Dietary vitamin E intake could reduce the risk of lung cancer: evidence from a meta-analysis.

Guohan Chen, Jinyi Wang, Xuan Hong, Zhengjun Chai, Qinchuan Li

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Guohan ChenDepartment of Thoracic Surgery, East Hospital, Tongji University School of Medicine 150 Jimo Road, Shanghai 200120, China.
Jinyi WangDepartment of Thoracic Surgery, East Hospital, Tongji University School of Medicine 150 Jimo Road, Shanghai 200120, China.
Xuan HongDepartment of Thoracic Surgery, East Hospital, Tongji University School of Medicine 150 Jimo Road, Shanghai 200120, China.
Zhengjun ChaiDepartment of Thoracic Surgery, East Hospital, Tongji University School of Medicine 150 Jimo Road, Shanghai 200120, China.
Qinchuan LiDepartment of Thoracic Surgery, East Hospital, Tongji University School of Medicine 150 Jimo Road, Shanghai 200120, China.
Shanghai East Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuantification of the association between the intake of vitamin E and risk of lung cancer is still conflicting. Thus, we conducted a meta-analysis to summarize the evidence from epidemiological studies of vitamin E intake with the risk of lung cancer.

methodsPertinent studies were identified by a search in PubMed and Web of Knowledge up to October 2014. Random-effect model was used to combine study-specific results. Publication bias was estimated using Egger's regression asymmetry test.

resultsTen articles reporting 11 studies (10 prospective studies and 1 case-control studies) involving 4434 lung cancer cases were used in this meta-analysis. The combined relative risk (RR) of lung cancer associated with vitamin E intake was 0.858 (95% CI=0.742-0.991) overall, significant protective associations were also found in America population (RR=0.862, 95% CI=0.715-0.996) and prospective studies (RR=0.913, 95% CI=0.827-0.996). No publication bias was found.

conclusionsOur analysis indicated that vitamin E intake might decrease the risk of lung cancer, especially in America.

Indexed as

lung cancermeta-analysisVitamin E

Identifiers

PMID26131295
PMCPMC4483938
OpenAlexW2406383644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.