ArticlePharmacy practice
Pattern of drug therapy problems and interventions in ambulatory patients receiving antiretroviral therapy in Nigeria.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence, contributing factors, and interventions to reduce medication errors in outpatient and ambulatory settings: a systematic review.International journal of clinical pharmacy · 2023Pooled it
- Drug therapy-related problem management in Nigeria community pharmacy - process evaluation with simulated patient.BMC health services research · 2022Article
- Drug-related problems in Ethiopian public healthcare settings: Systematic review and meta-analysis.SAGE open medicine · 2021Review
- Drug therapy problems identified among patients receiving antiretroviral treatment in a HIV clinic: a prospective study in North Central, Nigeria.The Pan African medical journal · 2021Article
- Drug Therapy Problems and the Role of Clinical Pharmacist in Surgery Ward: Prospective Observational and Interventional Study.Drug, healthcare and patient safety · 2020Article
- Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experienceTurkish journal of medical sciences · 2019Article
- HIV pharmaceutical care in primary healthcare: Improvement in CD4 count and reduction in drug-related problems.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2017Article
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9 authors.
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Abstract
objectivesWe describe the frequency and types of drug therapy problems (DTPs), and interventions carried out to resolve them, among a cohort of HIV-infected patients on ART in Jos, Nigeria.
methodsA prospective pharmacists' intervention study was conducted between January and August 2012 at the outpatient HIV clinic of the Jos University Teaching Hospital (JUTH). Pharmacists identified DTPs and made recommendations to resolve them. The main outcome measures were number of DTPs encountered, interventions proposed and acceptance rate of recommendations.
resultsA total of 42,416 prescriptions were dispensed to 9339 patients during the eight months study. A total of 420 interventions (Intervention rate of 1 per 100 prescriptions) were made to resolve DTPs in 401 (4.3%) patients with a mean age of 41 (SD=10) years, and made up of 73% females. DTPs encountered were drug omission (n=89, 21.2%), unnecessary drug (n=55, 13.1%) and wrong drug indication (n=55, 13.1%). Recommendations offered included; Addition of another drug to the therapy (n=87, 20.7%), rectification of incomplete prescriptions (n=85, 20.2%), change of drug or dosage (n=67, 16.0%), and discontinuation of the offending drug (n=59, 14.0%). A total of 389 (93%) out of 420 of the recommendations were accepted. In all, 50.4% (212) of the problematic prescriptions were changed and dispensed, 22.2% (89) were clarified and dispensed, while wrong identities were corrected in 11.7% (49). However, 7.5% (30) prescriptions were dispensed as prescribed, 5.2% (21) were not dispensed, and 3% (12) were unresolved.
conclusionOur findings suggest that pharmacists-initiated interventions can ameliorate DTPs in patients receiving ART given the high intervention acceptance rate recorded. The implication of this finding is that pharmacists with requisite training in HIV pharmacotherapy are an excellent resource in detecting and minimizing the effect of antiretroviral drug-related errors.
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